Gene

htr2cl1

ID

ZDB-GENE-081104-48

Name

5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1

Symbol

htr2cl1 Nomenclature History

Previous Names

si:dkey-24g18.2

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; release of sequestered calcium ion into cytosol; and response to drug. Predicted to localize to dendrite and integral component of plasma membrane. Is expressed in integument; nervous system; ovary; and skeletal muscle. Human ortholog(s) of this gene implicated in bipolar disorder; obesity; and schizophrenia. Orthologous to human HTR2C (5-hydroxytryptamine receptor 2C).

Genome Resources

Note

None

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

No data available

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With htr2cl1 Human Ortholog

No data available

Associated With htr2cl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR000377	5-Hydroxytryptamine 2C receptor
Family	IPR002231	5-hydroxytryptamine receptor family