Gene

slc6a3

ID
ZDB-GENE-010316-1
Name
solute carrier family 6 member 3
Symbol
slc6a3 Nomenclature History
Previous Names
  • DAT (1)
  • dat (1)
  • dopamine transporter (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have symporter activity. Predicted to localize to integral component of membrane. Is expressed in several structures, including dopaminergic neurons; forebrain; male organism; medulla oblongata; and retina. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; nicotine dependence; and obesity. Orthologous to human SLC6A3 (solute carrier family 6 member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
59 figures from 46 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc6a3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Parkinsonism-dystonia, infantile, 1 613135
{Nicotine dependence, protection against} 188890
Associated With slc6a3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000175 Sodium:neurotransmitter symporter
Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
Domain Details Per Protein
Protein Length Sodium:neurotransmitter symporter Sodium:neurotransmitter symporter superfamily
UniProtKB:Q90ZV1 629
UniProtKB:F1QGM4 629
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations