Gene

slc6a3

ID
ZDB-GENE-010316-1
Name
solute carrier family 6 member 3
Symbol
slc6a3 Nomenclature History
Previous Names
  • DAT (1)
  • dat (1)
  • dopamine transporter (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have symporter activity. Predicted to localize to integral component of membrane. Is expressed in several structures, including dopaminergic neurons; forebrain; male organism; medulla oblongata; and retina. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; nicotine dependence; and obesity. Orthologous to human SLC6A3 (solute carrier family 6 member 3).
Genome Resources
Note
None
Expression
All Expression Data
58 figures from 45 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc6a3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Parkinsonism-dystonia, infantile, 1 613135
{Nicotine dependence, protection against} 188890
Associated With slc6a3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000175 Sodium:neurotransmitter symporter
Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
Domain Details Per Protein
Protein Length Sodium:neurotransmitter symporter Sodium:neurotransmitter symporter superfamily
UniProtKB:F1QGM4 629
UniProtKB:Q90ZV1 629
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations