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General Information
ZIRC
ZFIN ID: ZDB-GENE-090312-91
Gene Name: cholinergic receptor, nicotinic, alpha 6
Gene Symbol: chrna6    Nomenclature History

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Previous Name: si:dkey-234d14.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to contribute to acetylcholine binding activity; acetylcholine receptor activity; and extracellular ligand-gated ion channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; regulation of membrane potential; and response to nicotine. Predicted to localize to the acetylcholine-gated channel complex; neuron projection; and synapse. Is expressed in immature eye and nervous system. Orthologous to human CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit).
Genome Resources: Alliance (1),  Gene:555747 (1),  Ensembl(GRCz11):ENSDARG00000055559 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15480 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko426a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko426b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-chrna6 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chrna6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chrna6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transmembrane transport (more)
    Cellular Component cell junction (more)
    Molecular Function acetylcholine-gated cation-selective channel activity (more)
    GO Terms (all 24)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chrna6-201 (1)    Ensembl 1937
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chrna6 No data available
    MARKER RELATIONSHIPS
    chrna6 Contained in: [BAC] CH211-240P12 (1) (order this), DKEY-234D14 (1) (order this)
    chrna6 Encodes: [cDNA] MGC:198130 (1) (order this), MGC:198132 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001042684 (1) 1940 bp
    Genomic GenBank:CR376846 (1) 145408 bp
    Select Tool
    Polypeptide UniProtKB:F1QR92 (1) 512 aa
    Sequence Clusters UniGene:72302 (1)
    Sequence Information (all 19)
    ORTHOLOGY for chrna6 ( Chr: 1 )
    CITATIONS (25)