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General Information
ZIRC
ZFIN ID: ZDB-GENE-040108-3
Gene Name: cholinergic receptor, nicotinic, alpha 7 (neuronal)
Gene Symbol: chrna7
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Contributes to acetylcholine receptor activity. Involved in response to nicotine. Localizes to the acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in schizophrenia.  ...
GENE EXPRESSION
All Expression Data: text only from Zirger et al., 2003
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2371 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21086 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21087 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chrna7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chrna7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to nicotine (more)
    Cellular Component acetylcholine-gated channel complex (more)
    Molecular Function CONTRIBUTES_TO acetylcholine receptor activity (more)
    GO Terms (all 23)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA chrna7-201 (1) 1612
    ottdart00000002167 (1) 1524
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM chrna7 No data available
    MARKER RELATIONSHIPS
    chrna7Contained in: [BAC] DKEY-215P16 (1) (order this)
    [PAC] BUSM1-70B1 (order this)
    chrna7Contains: [STS] chunp40143 (1)
    chrna7Encodes: [cDNA] MGC:193874 (1) (order this), MGC:193893 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201219 (1) 1719bp
    Genomic GenBank:AL928677 (1) 144076bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IV47 (1) 510aa
    Sequence Clusters UniGene:29390 (1)
    Sequence Information (all 21)
    ORTHOLOGY for chrna7 (Chr: 7)
    CITATIONS (32)