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Gene

chrna7a

ID
ZDB-GENE-040108-3
Name
cholinergic receptor, nicotinic, alpha 7a (neuronal)
Symbol
chrna7a Nomenclature History
Previous Names
  • chrna7
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Contributes to acetylcholine receptor activity. Acts upstream of or within response to nicotine. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chrna7a Human Ortholog
No data available
Associated With chrna7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018000 Neurotransmitter-gated ion-channel, conserved site
Domain IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Domain IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain
Family IPR002394 Nicotinic acetylcholine receptor
Family IPR006201 Neurotransmitter-gated ion-channel
Homologous_superfamily IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamily
Homologous_superfamily IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Domain Details Per Protein
Protein Length Neurotransmitter-gated ion-channel Neurotransmitter-gated ion-channel, conserved site Neurotransmitter-gated ion-channel ligand-binding domain Neurotransmitter-gated ion-channel ligand-binding domain superfamily Neurotransmitter-gated ion-channel transmembrane domain Neurotransmitter-gated ion-channel transmembrane domain superfamily Nicotinic acetylcholine receptor
UniProtKB:B3DH13 509
UniProtKB:Q6ZM45 507
UniProtKB:Q800C7 509
UniProtKB:A0A0R4IV47 510
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations