ZFIN ID: ZDB-GENE-021119-1
Gene Name: dopamine receptor D3
Gene Symbol: drd3
Location: Chr: 24 Details
GENE EXPRESSION
All Expression Data: Fig. 7 from Boehmler et al., 2004
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, diencephalon, hindbrain, hindbrain nucleus (all 11) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa15862 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: CRISPR1-drd3 (2), CRISPR2-drd3 (1), CRISPR3-drd3 (1), TALEN1-drd3 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH drd3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    essential tremor {Essential tremor, susceptibility to} 190300
    schizophrenia {Schizophrenia, susceptibility to} 181500
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G-protein coupled receptor signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function G-protein coupled receptor activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000276 (1)
  • InterPro:IPR000929 (1)
  • InterPro:IPR001620 (1)
  • InterPro:IPR017452 (1)
  • PROSITE:PS00237 (1)
  • PROSITE:PS50262 (1)
  • Pfam:PF00001 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA drd3-001 (1) 2285
    drd3-002 (1) 1400
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM drd3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    drd3Contained in: [BAC] CH73-50O14 (1) (order this), CH211-72H10 (1) (order this)
    drd3Encodes: [cDNA] MGC:92896 (1) (order this), MGC:192815 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_183067 (1) 1400bp
    Genomic GenBank:CT956069 (1) 137539bp
    Select Tool
    Polypeptide UniProtKB:F1QG18 (1) 472aa
    Sequence Clusters UniGene:151864 (1)
    Sequence Information (all 20)
    OTHER drd3 GENE PAGES
  • Gene:282554 (1)
  • VEGA:OTTDARG00000028609 (1)
  • Ensembl(GRCz10):ENSDARG00000032131 (1)
  • ORTHOLOGY for drd3 (Chr: 24)
    Species Symbol Chromosome Accession # Evidence
    Human DRD3 3
  • Gene:1814
  • OMIM:126451
  • HGNC:3024
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Drd3 16
  • MGI:94925
  • Gene:13490
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (27)