Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-021119-1
Gene Name: dopamine receptor D3
Gene Symbol: drd3
Location: Chr: 24   Details
GENE EXPRESSION
All Expression Data: Fig. 7 from Boehmler et al., 2004
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, diencephalon, hindbrain, hindbrain nucleus (all 11) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa15862
Knockdown reagents: CRISPR1-drd3 (1), CRISPR2-drd3 (1), CRISPR3-drd3 (1), TALEN1-drd3 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
{Essential tremor, susceptibility to} 190300
{Schizophrenia, susceptibility to} 181500
GENE ONTOLOGY
Ontology GO Term
Biological Process G-protein coupled receptor signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function G-protein coupled receptor activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000276 (1)
  • InterPro:IPR000929 (1)
  • InterPro:IPR001620 (1)
  • InterPro:IPR017452 (1)
  • PROSITE:PS00237 (1)
  • PROSITE:PS50262 (1)
  • Pfam:PF00001 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA drd3-001 (1) 2285
    drd3-002 (1) 1400
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM drd3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    drd3 Contained in: [BAC] CH73-50O14 (1) (order this), CH211-72H10 (1) (order this)
    drd3 Encodes: [cDNA] MGC:92896 (1) (order this), MGC:192815 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_183067 (1) 1400 bp
    Genomic GenBank:CT956069 (1) 137539 bp
    Select Tool
    Polypeptide UniProtKB:F1QG18 (1) 472 aa
    Sequence Clusters UniGene:151864 (1)
    Sequence Information (all 20)
    OTHER drd3 GENE PAGES
  • Gene:282554 (1)
  • VEGA:OTTDARG00000028609 (1)
  • Ensembl(Zv9):ENSDARG00000032131 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish drd3 24  
    Human DRD3 3 (3q13.3)
  • OMIM:126451
  • Gene:1814
  • Mouse Drd3 16 ( 28.44 cM)
  • MGI:94925
  • Gene:13490
  • Orthology Details
    CITATIONS (23)