Gene
drd2a
- ID
- ZDB-GENE-021119-2
- Name
- dopamine receptor D2a
- Symbol
- drd2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have adrenergic receptor activity; dopamine binding activity; and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; behavioral response to cocaine; and regulation of ion transport. Predicted to localize to integral component of plasma membrane and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in several diseases, including brain disease (multiple); end stage renal failure; mental depression; obesity; and type 2 diabetes mellitus. Is expressed in nervous system. Orthologous to human DRD2 (dopamine receptor D2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dopamine D2 receptor | Dopamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B0Z4
|
420 | ||||
|
UniProtKB:Q8AWE0
|
448 |
Interactions and Pathways
No data available
Plasmids
No data available