Gene

adra2b

ID
ZDB-GENE-021010-2
Name
adrenoceptor alpha 2B
Symbol
adra2b Nomenclature History
Previous Names
  • fb43d01
  • wu:fb43d01 (1)
  • zgc:194747
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Exhibits alpha2-adrenergic receptor activity. Involved in adenylate cyclase-inhibiting adrenergic receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including digestive system; eye; heart; integument; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in diabetic neuropathy; hypertension; myocardial infarction; obesity; and type 2 diabetes mellitus. Orthologous to human ADRA2B (adrenoceptor alpha 2B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adra2b Human Ortholog
No data available
Associated With adra2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:Q90WY5 510
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations