- Title
-
The Warburg Effect and lactate signaling augment Fgf-MAPK to promote sensory-neural development in the otic vesicle
- Authors
- Kantarci, H., Gou, Y., Riley, B.B.
- Source
- Full text @ Elife
Initial analysis of sagd1.PHENOTYPE:
|
Quantitation of mature Isl1/2+ SAG neurons and TUNEL in sagd1 mutants. |
Sensory development and early Fgf signaling are impaired in sagd1 mutants.EXPRESSION / LABELING:
PHENOTYPE:
|
Two independent transcripts associated with the pgk1 locus. |
ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
|
Expression of pgk1-FL during development.EXPRESSION / LABELING:
PHENOTYPE:
|
pgk1-alt misexpression increases pgk1 transcript abundance. |
Initial characterization of pgk1- / - mutants and genetic mosaics.EXPRESSION / LABELING:
PHENOTYPE:
|
( |
( |
( |
ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
|
( |
ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
|
ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
|
Exogenous lactate reverses the effects of disrupting aerobic glycolysis.EXPRESSION / LABELING:
PHENOTYPE:
|
Dorsolateral view (anterior to the left) of the otic vesicle (outlined) showing expression of |
( EXPRESSION / LABELING:
PHENOTYPE:
|
Unillustrated author statements PHENOTYPE:
|