Gene

otx1

ID
ZDB-GENE-980526-400
Name
orthodenticle homeobox 1
Symbol
otx1 Nomenclature History
Previous Names
  • otx1
  • otx1b
  • zOtx1 (1)
  • cb769 (1)
  • fj99f05 (1)
  • wu:fj99f05
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in inner ear morphogenesis; lateral semicircular canal development; and retinal pigment epithelium development. Predicted to localize to nucleus. Is expressed in several structures, including germ ring; immature eye; nervous system; neural keel; and presumptive neural plate. Orthologous to human OTX1 (orthodenticle homeobox 1).
Genome Resources
Note
None
Expression
All Expression Data
59 figures from 35 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With otx1 Human Ortholog
No data available
Associated With otx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR013851 Transcription factor Otx, C-terminal
Family IPR003025 Transcription factor Otx
Family IPR003026 Transcription factor Otx1
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Transcription factor Otx Transcription factor Otx1 Transcription factor Otx, C-terminal
UniProtKB:B2GNW8 323
UniProtKB:Q91994 323
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations