Gene
neurog1
- ID
- ZDB-GENE-990415-174
- Name
- neurogenin 1
- Symbol
- neurog1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding activity; and chromatin binding activity. Involved in generation of neurons; hindbrain morphogenesis; and peripheral nervous system development. Acts upstream of or within several processes, including negative regulation of neurogenesis; nervous system development; and olfactory placode development. Predicted to be active in nucleus. Is expressed in several structures, including ectoderm; nervous system; neural keel; neural rod; and neural tube. Orthologous to human NEUROG1 (neurogenin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 266 figures from 169 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb260 (37 images)
Wild Type Expression Summary
- All Phenotype Data
- 26 figures from 17 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cranial dysinnervation disorder, congenital, with absent corneal reflex and developmental delay | 620469 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Basic helix-loop-helix transcription factors | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|---|
| UniProtKB:O42606 | InterPro | 208 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
neurog1-201
(1)
|
Ensembl | 1,393 nt |
Interactions and Pathways
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-neurog1 | polyclonal | Mouse |
|
Abcam plc
|
1 |
Plasmids
No data available