ZFIN is now using GRCz12tu for Genomic Data
Gene
fgf3
- ID
- ZDB-GENE-980526-178
- Name
- fibroblast growth factor 3
- Symbol
- fgf3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables fibroblast growth factor receptor binding activity. Acts upstream of with a negative effect on Wnt signaling pathway. Acts upstream of or within with a positive effect on hypothalamus development. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and positive regulation of cell differentiation. Located in extracellular matrix and extracellular space. Is expressed in several structures, including brain; mesoderm; neural rod; pharynx; and sensory system. Orthologous to human FGF3 (fibroblast growth factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 145 figures from 108 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 32 figures from 17 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Deafness, congenital with inner ear agenesis, microtia, and microdontia | 610706 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|---|
| UniProtKB:P48802 | InterPro | 256 | ||
| UniProtKB:B3DHR1 | InterPro | 256 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers