ZFIN ID: ZDB-GENE-980526-178
Gene Name: fibroblast growth factor 3
Gene Symbol: fgf3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: id:ibd5006 (1), lia (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits fibroblast growth factor receptor binding activity. Involved in several processes, including animal organ development; nervous system development; and regionalization. Localizes to the extracellular matrix and extracellular space. Is expressed in several structures, including germ ring; mesoderm; nervous system; neural rod; and pharynx. Orthologous to human FGF3 (fibroblast growth factor 3).
Genome Resources: Alliance (1),  Gene:30549 (1),  Ensembl(GRCz11):ENSDARG00000101540 (1)
GENE EXPRESSION
All Expression Data: 125 figures from 94 publications
Directly Submitted Expression Data: 5 figures (9 images) from Kudoh et al., 2001 [ibd5006]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fgf3_unspecified Unspecified Unknown Unknown
psi60Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
t21142 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • t24149 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • t24152 Point Mutation Unknown Unknown ENU
    t26212 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • y323Et Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fgf3 1
    CRISPR2-fgf3
    1
    CRISPR3-fgf3
    1
    MO1-fgf3 N/A 27
    MO2-fgf3 N/A 9
    MO3-fgf3 N/A 7
    MO4-fgf3 N/A 6
    MO5-fgf3 N/A 7
    MO6-fgf3 N/A 1
    MO7-fgf3 N/A 1
    MO8-fgf3 N/A 3
    MO9-fgf3 N/A 1
    DISEASE ASSOCIATED WITH fgf3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Deafness, congenital with inner ear agenesis, microtia, and microdontia 610706
    DISEASE ASSOCIATED WITH fgf3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior pattern specification (more)
    Cellular Component extracellular matrix (more)
    Molecular Function fibroblast growth factor receptor binding (more)
    GO Terms (all 46)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR002209 Fibroblast growth factor family
    Family IPR028232 Fibroblast growth factor 3
    Homologous_superfamily IPR008996 Cytokine IL1/FGF
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fgf3-201 (1)    Ensembl 1887
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fgf3
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tg(fgf3:hsa.hist1h2bj-mturquoise2) fgf3 mTurquoise Danio rerioHomo sapiens 0 2
    Tg(hsp70l:fgf3) hsp70l fgf3 Danio rerio 1 2
    Tg(hsp70l:fgf3-MYC) hsp70l fgf3 Danio rerio 1 11
    Tg(LEXOP:sGFP-fgf3,myl7:EGFP) LEXOPmyl7 EGFPfgf3sGFP Danio rerio 1 1
    Tg(UAS:fgf3,myl7:EGFP) myl7UAS EGFPfgf3 Danio rerio 1 1
    Tg1(hsp70l:fgf3) hsp70l fgf3 Danio rerio 1 5
    TgBAC(fgf3:fgf3-sGFP,cryaa:CFP) cryaafgf3 CFPfgf3sGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    fgf3 Contained in: [BAC] CH211-96B20 (1)
    fgf3 Encodes: [EST] ibd5006 (1)
    [cDNA] MGC:194262 (1), MGC:194301 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131291 (1) 771 nt
    Genomic GenBank:CU896555 (1) 153440 nt
    Select Tool
    Polypeptide UniProtKB:B3DHR1 (1) 256 aa
    Sequence Information (all 19)
    ORTHOLOGY for fgf3 ( Chr: 7 )
    CITATIONS (231)