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ZIRC
ZFIN ID: ZDB-GENE-991228-4
Gene Name: ETS variant transcription factor 5b
Gene Symbol: etv5b    Nomenclature History

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Previous Names: cb805 (1), erm1 (1), erm, wu:fe05h04, wu:fj66a04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including limb morphogenesis; nervous system development; and pronephros development. Predicted to localize to the nucleus. Is expressed in several structures, including brain; eye; mesoderm; neural plate; and pharyngeal arch. Orthologous to human ETV5 (ETS variant transcription factor 5).
Genome Resources: Alliance (1),  Gene:30452 (1),  Ensembl(GRCz11):ENSDARG00000044511 (1)
GENE EXPRESSION
All Expression Data: 78 figures from 59 publications
Directly Submitted Expression Data: 6 figures (34 images) from Thisse et al., 2001 [cb805]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029178Tg Transgenic Insertion Unknown Unknown DNA
sa30870 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40656 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-etv5b N/A 3
    MO2-etv5b N/A 3
    MO3-etv5a,etv5b N/A 1
    MO3-etv5b N/A 2
    MO4-etv5a,etv5b N/A 1
    DISEASE ASSOCIATED WITH etv5b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH etv5b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process limb morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA etv5b-201 (1)    Ensembl 2837
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM etv5b
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-5etv5b:GAL4-VP16) etv5b GAL4VP16 Danio rerio 1 5
    MARKER RELATIONSHIPS
    etv5b Contained in: [BAC] DKEY-29F19 (1) (order this), DKEYP-78G2 (1)
    etv5b Encodes: [EST] cb805 (1) (order this), fe05h04, fj66a04
    [cDNA] MGC:73250 (1) (order this), MGC:173964 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131205 (1) 2779 bp
    Genomic GenBank:BX323042 (1) 206473 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QC01 (1) 526 aa
    Sequence Clusters UniGene:7714 (1)
    Sequence Information (all 37)
    ORTHOLOGY for etv5b ( Chr: 6 )
    CITATIONS (126)