Gene
fgf8a
- ID
- ZDB-GENE-990415-72
- Name
- fibroblast growth factor 8a
- Symbol
- fgf8a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have fibroblast growth factor receptor binding activity and growth factor activity. Involved in several processes, including animal organ development; determination of bilateral symmetry; and nervous system development. Localizes to extracellular space and lysosome. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 6 with or without anosmia and prostate carcinoma in situ. Is expressed in several structures, including germ ring; head; mesoderm; nervous system; and neural keel. Orthologous to human FGF8 (fibroblast growth factor 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 340 figures from 267 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb110 (100 images)
Wild Type Expression Summary
- All Phenotype Data
- 72 figures from 45 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 6 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 6 with or without anosmia | 612702 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|
|
UniProtKB:O57341
|
210 |
Interactions and Pathways
Plasmids