Gene

pou3f3b

ID
ZDB-GENE-980526-140
Name
POU class 3 homeobox 3b
Symbol
pou3f3b Nomenclature History
Previous Names
  • pou1
  • pou23
  • zp23
  • fb92g06
  • wu:fb92g06 (1)
  • zfpou1 (1)
  • zp23pou
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Is expressed in nervous system; neural rod; otic vesicle; pronephric duct; and spinal cord neural tube. Human ortholog(s) of this gene implicated in X-linked deafness 2. Orthologous to several human genes including POU3F3 (POU class 3 homeobox 3).
Genome Resources
Note
None
Expression
All Expression Data
15 figures from 10 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pou3f3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Snijders Blok-Fisher syndrome 618604
Associated With pou3f3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR000327 POU-specific domain
Domain IPR001356 Homeobox domain
Domain IPR013847 POU domain
Family IPR016362 POU-domain transcription factor, class 3
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Lambda repressor-like, DNA-binding domain superfamily POU domain POU-domain transcription factor, class 3 POU-specific domain
UniProtKB:P79745 443
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations