ZFIN ID: ZDB-TGCONSTRCT-101007-1
Transgenic Construct Name: Tg(ZM)
Sequence Ontology ID :
Synonym: ZM

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Note: Znomics retroviral construct 5.2kb long. Methods described in  Amsterdam and Hopkins 2006 and Jao et al. 2008 The viral construct contains the core viral components, e.g. long terminal repeats (LTRs) and a packaging signal and the gene activation cassette, which includes a polyadenylation signal (pA) from bovine growth hormone, fourteen tandemly repeated UAS14 sequences, and a synthetic element that includes a splice donor (SD).

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CONSTRUCT COMPONENTS
Contains: UAS (1)
GENOMIC FEATURES THAT UTILIZE Tg(ZM)
Genomic Feature Affected Genomic Regions    
hg8Tg opa3    
ipk1Tg slc22a21    
umc5Tg ocrl    
vu426Tg cdc14b    
vu442Tg kctd12.1    
zf157Tg tcf7l1b    
zm00012575Tg hes6    
zm00057434Tg brca2    
zm00075660Tg brca2    
zm00105646Tg gnptg    
zm00173004Tg dmrt1    
zm00177433Tg aplnra    
zm00260171Tg ewsr1a    
zm00416857Tg rnpc3    
zm00452188Tg crb2b    
zm130198Tg dcc    
zm197263Tg notch3    
zm5961Tg lta4h    
TRANSGENICS THAT UTILIZE Tg(ZM)
Fish Affected Genomic Regions Phenotype Gene Expression
aplnrazm00177433Tg/zm00177433Tg aplnra Fig. 1 with image from Deshwar et al., 2016 Fig. 1 with image from Deshwar et al., 2016
aplnrbhu4145/hu4145 ; aplnrazm00177433Tg/zm00177433Tg aplnra, aplnrb 4 figures with image from Deshwar et al., 2016 4 figures with image from Deshwar et al., 2016
aplnrbhu4145/hu4145 ; aplnrazm00177433Tg/zm00177433Tg + MO3-lft1 Fig. 3 with image from Deshwar et al., 2016 Fig. 3 with image from Deshwar et al., 2016
brca2zf1074/+ ; brca2zm00057434Tg/+ brca2 Fig. 8 with image from Kroeger et al., 2017 Fig. 8 with image from Kroeger et al., 2017
brca2zm00057434Tg/+ ; brca2zf1074/+ brca2 text only from Drummond et al., 2018
brca2zm00057434Tg/zm00057434Tg brca2 5 figures with image from Rodriguez-Mari et al., 2011 Fig. 6 with image from Rodriguez-Mari et al., 2011
brca2zm00057434Tg brca2 Fig. 8 with image from Rodriguez-Mari et al., 2011
cdc14bvu426Tg/vu426Tg cdc14b Fig. 1 with image from Clément et al., 2011
cdc14bvu426Tg/vu426Tg + MO1-cdc14aa 2 figures with image from Clément et al., 2012
cdc14bvu426Tg/vu426Tg + MO2-cdc14aa Fig. 2 with image from Clément et al., 2012
cdc14bvu426Tg/vu426Tg; twu34Tg cdc14b Fig. 2 with image from Clément et al., 2011
cdc14bvu426Tg/vu426Tg; twu34Tg + MO1-cdc14b Fig. 2 with image from Clément et al., 2011
crb2bzm00452188Tg/zm00452188Tg crb2b 3 figures from Ebarasi et al., 2015 Fig. 4 from Ebarasi et al., 2015
dcctm272b/+ ; dcczm130198Tg/+(TL) dcc Fig. 2 from Jain et al., 2014
dcczm130198Tg/zm130198Tg(TL) dcc 2 figures from Jain et al., 2014 Fig. 1 from Jain et al., 2014
dcczm130198Tg/zm130198Tg ; j1229aGt(TL) dcc Fig. 4 from Jain et al., 2014
dcczm130198Tg/zm130198Tg; ml2Tg dcc Fig. 8 from Rosenberg et al., 2014 Fig. 8 from Rosenberg et al., 2014
dmrt1zm00173004Tg/+ dmrt1 Fig. 6 from Webster et al., 2017
dmrt1zm00173004Tg/+ + MO1-dnd1 Fig. 6 from Webster et al., 2017
dmrt1zm00173004Tg/zm00173004Tg dmrt1 2 figures with image from Webster et al., 2017 2 figures with image from Webster et al., 2017
dmrt1zm00173004Tg/zm00173004Tg + MO1-dnd1 Fig. 3 from Webster et al., 2017 Fig. 6 from Webster et al., 2017
ewsr1azm00260171Tg/zm00260171Tg ewsr1a 3 figures with image from 2 publications 3 figures with image from Merkes et al., 2015
gnptgzm00105646Tg/+ gnptg Fig. 3 from Flanagan-Steet et al., 2016
gnptgzm00105646Tg/zm00105646Tg gnptg Fig. 1 from Flanagan-Steet et al., 2016 Fig. 1 from Flanagan-Steet et al., 2016
gnptgzm00105646Tg/zm00105646Tg; y1Tg gnptg 2 figures from Flanagan-Steet et al., 2016 2 figures from Flanagan-Steet et al., 2016
her1hu2124/hu2124; hes6zm00012575Tg/zm00012575Tg her1, hes6
hes6zm00012575Tg/+(AB) hes6 Fig. S1 with image from Schröter et al., 2010
hes6zm00012575Tg/zm00012575Tg(AB) hes6 4 figures with image from Schröter et al., 2010 4 figures with image from Schröter et al., 2010
hes6zm00012575Tg/zm00012575Tg + MO1-her1 + MO3-her1 Fig. 1 with image from Schröter et al., 2010 Fig. 1 with image from Schröter et al., 2010
hes6zm00012575Tg/zm00012575Tg + MO3-hes6(AB) Fig. S1 with image from Schröter et al., 2010 Fig. S1 with image from Schröter et al., 2010
kctd12.1vu442Tg/vu442Tg(AB) kctd12.1 Fig. 7 from Taylor et al., 2011 2 figures from Taylor et al., 2011
kctd12.1vu442Tg/vu442Tg + MO2-ulk2(AB) Fig. 9 from Taylor et al., 2011 Fig. 9 from Taylor et al., 2011
kctd12.1vu442Tg/vu442Tg ; kctd12.2fh312/fh312 kctd12.1, kctd12.2 Fig. 4 from Lee et al., 2014
kctd12.2fh312/fh312; kctd12.1vu442Tg/vu442Tg(AB) kctd12.1, kctd12.2 Fig. 7 from Taylor et al., 2011 Fig. 7 from Taylor et al., 2011
lta4hzm5961Tg/zm5961Tg lta4h Fig. S2 with image from Tobin et al., 2010
notch3st51/+; notch3zm197263Tg/+ notch3 Fig. 1 with image from Zaucker et al., 2013
notch3zm197263Tg/+ notch3 3 figures with image from Zaucker et al., 2013
notch3zm197263Tg/+; y1Tg notch3 Fig. 2 with image from Zaucker et al., 2013
notch3zm197263Tg/zm197263Tg notch3 4 figures with image from Zaucker et al., 2013 3 figures with image from Zaucker et al., 2013
notch3zm197263Tg/zm197263Tg; y1Tg notch3 Fig. 2 with image from Zaucker et al., 2013
ocrlumc5Tg/umc5Tg ocrl 19 figures with image from 4 publications 6 figures with image from 2 publications
ocrlumc5Tg/umc5Tg + MO2-ift88 Fig. 7 with image from Oltrabella et al., 2015
ocrlumc5Tg/umc5Tg; mw5Tg ocrl Fig. 2 with image from Oltrabella et al., 2015
ocrlumc5Tg/umc5Tg; mw7Tg ocrl 2 figures with image from Oltrabella et al., 2015
ocrlumc5Tg/umc5Tg; p152Tg ocrl Fig. S3 with image from Oltrabella et al., 2015 Fig. S3 with image from Oltrabella et al., 2015
opa3hg8Tg/hg8Tg opa3 5 figures with image from Pei et al., 2010
rnpc3s846/+; rnpc3zm00416857Tg/+ rnpc3 Fig. S1 with image from Markmiller et al., 2014
rnpc3zm00416857Tg/zm00416857Tg rnpc3 Fig. S1 with image from Markmiller et al., 2014 Fig. S2 with image from Markmiller et al., 2014
slc22a21ipk1Tg/ipk1Tg(EKW) slc22a21 2 figures from Pfeiffer et al., 2015
slc22a21ipk1Tg(EKW) slc22a21
tcf7l1am881/m881; tcf7l1bzf157Tg/zf157Tg tcf7l1a, tcf7l1b text only from Gribble et al., 2009
tp53zdf1/+; ewsr1azm00260171Tg/+ ewsr1a, tp53 Fig. 1 with image from Park et al., 2016
tp53zdf1/+; ewsr1azm00260171Tg/zm00260171Tg ewsr1a, tp53 Fig. 1 with image from Park et al., 2016
tp53zdf1/zdf1; brca2zm00057434Tg/zm00057434Tg brca2, tp53 3 figures with image from Rodriguez-Mari et al., 2011
tp53zdf1/zdf1; ewsr1azm00260171Tg/+ ewsr1a, tp53 Fig. 1 with image from Park et al., 2016
tp53zdf1/zdf1; ewsr1azm00260171Tg/zm00260171Tg ewsr1a, tp53 Fig. 1 with image from Park et al., 2016
SEQUENCE INFORMATION No data available
OTHER Tg(ZM) TRANSGENIC CONSTRUCT PAGES
CITATIONS (41)