Gene

opa3

ID
ZDB-GENE-050210-1
Name
outer mitochondrial membrane lipid metabolism regulator OPA3
Symbol
opa3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Involved in locomotory behavior; musculoskeletal movement; and regulation of buoyancy. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 3 and optic atrophy 3. Is expressed in heart; liver; nervous system; and pleuroperitoneal region. Orthologous to human OPA3 (outer mitochondrial membrane lipid metabolism regulator OPA3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Pei et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With opa3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
3-methylglutaconic aciduria type 3 Alliance 3-methylglutaconic aciduria, type III 258501
optic atrophy 3 Alliance Optic atrophy 3 with cataract 165300
Associated With opa3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010754 Optic atrophy 3-like
Domain Details Per Protein
Protein Length Optic atrophy 3-like
UniProtKB:Q1L9A2 157
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations