Gene

tcf7l1b

ID
ZDB-GENE-991110-10
Name
transcription factor 7 like 1b
Symbol
tcf7l1b Nomenclature History
Previous Names
  • tcf3b (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell proliferation in dorsal spinal cord; endothelial cell fate specification; and nervous system development. Predicted to localize to beta-catenin-TCF complex. Is expressed in nervous system; optic vesicle; and posterior neural tube. Orthologous to human TCF7L1 (transcription factor 7 like 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tcf7l1b Human Ortholog
No data available
Associated With tcf7l1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Domain IPR013558 CTNNB1 binding, N-teminal
Family IPR024940 Transcription factor TCF/LEF
Family IPR028778 Transcription factor 7-like 1
Homologous_superfamily IPR027397 Catenin binding domain superfamily
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length Catenin binding domain superfamily CTNNB1 binding, N-teminal High mobility group box domain High mobility group box domain superfamily Transcription factor 7-like 1 Transcription factor TCF/LEF
UniProtKB:B0S559 421
UniProtKB:Q800Q5 551
UniProtKB:F8W3L0 129
UniProtKB:F1R336 550
UniProtKB:A0A2R8RLK6 585
UniProtKB:Q9W7B8 287
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations