ZFIN ID: ZDB-GENE-040426-820
Gene Name: cell division cycle 14B
Gene Symbol: cdc14b    Nomenclature History

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Previous Names: cdc14a (1), zgc:55844 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Involved in cilium assembly. Localizes to condensed chromosome; nucleolus; and spindle. Is expressed in EVL and proliferative region. Orthologous to several human genes including CDC14B (cell division cycle 14B).
Genome Resources: Alliance (1),  Gene:393148 (1),  Ensembl(GRCz11):ENSDARG00000021483 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:55844]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026336Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21171 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu426Tg Transgenic Insertion Intron 1 Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cdc14b N/A 2
    MO2-cdc14b N/A 1
    MO3-cdc14b N/A 1
    DISEASE ASSOCIATED WITH cdc14b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cdc14b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium assembly (more)
    Cellular Component NOT   centrosome (more)
    Molecular Function phosphatase activity (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript cdc14b-203 (1)    Ensembl 851
    antisense ottdart00000059745 (1) 1356
    mRNA cdc14b-202 (1)    Ensembl 863
    cdc14b-204 (1)    Ensembl 868
    cdc14b-205 (1)    Ensembl 1484
    cdc14b-206 (1)    Ensembl 2055
    ncRNA cdc14b-005 (1)    Ensembl 782
    cdc14b-006 (1)    Ensembl 1030
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdc14b No data available
    MARKER RELATIONSHIPS
    cdc14b Contained in: [BAC] CH73-129K1 (1)
    [Fosmid] CH1073-145E6 (1)
    cdc14b Encodes: [cDNA] MGC:55844 (1), MGC:192648 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200179 (1) 1991 nt
    Genomic GenBank:CU896541 (1) 104170 nt
    Select Tool
    Polypeptide UniProtKB:F8W2B2 (1) 476 aa
    Sequence Information (all 35)
    ORTHOLOGY for cdc14b ( Chr: 8 )
    CITATIONS (30)