Gene
rnpc3
- ID
- ZDB-GENE-060312-35
- Name
- RNA-binding region (RNP1, RRM) containing 3
- Symbol
- rnpc3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have U12 snRNA binding activity and pre-mRNA intronic binding activity. Involved in animal organ development; digestive tract development; and mRNA splicing, via spliceosome. Predicted to localize to U12-type spliceosomal complex. Human ortholog(s) of this gene implicated in isolated growth hormone deficiency. Is expressed in digestive system; pharyngeal arch; post-vent region; proliferative region; and sensory system. Orthologous to human RNPC3 (RNA binding region (RNP1, RRM) containing 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Markmiller et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined or isolated pituitary growth hormone deficiency 7 | Alliance | Pituitary hormone deficiency, combined or isolated, 7 | 618160 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR034147 | RBM40, RNA recognition motif 1 |
| Family | IPR045164 | RNA-binding region-containing protein RBM41/RNPC3 |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RBM40, RNA recognition motif 1 | RNA-binding domain superfamily | RNA-binding region-containing protein RBM41/RNPC3 | RNA recognition motif domain |
|---|---|---|---|---|---|---|
|
UniProtKB:F1Q8J0
|
505 |
Interactions and Pathways
No data available
Plasmids
No data available