ZFIN

ZFIN ID: ZDB-GENE-030131-2935

ZFIN ID: ZDB-GENE-030131-2935

CITATIONS (107 total)

Gene Name:	insulin-like growth factor 2b
Gene Symbol:	igf2b

Zebrafish Nomenclature Committee (2025) Nomenclature Data Curation (2025). Nomenclature Committee Submission.

Ka, Y., Lee, I., Ji, K. (2024) Thyroid and growth hormone endocrine disruption and mechanisms of homosalate and octisalate using wild-type, thrαa^-/-, and dre-miR-499^-/- zebrafish embryo/larvae. Ecotoxicology and environmental safety. 286:117170117170

Heidary, S., Awasthi, N., Page, N., Allnutt, T., Lewis, R.S., Liongue, C., Ward, A.C. (2023) A zebrafish model of growth hormone insensitivity syndrome with immune dysregulation 1 (GHISID1). Cellular and molecular life sciences : CMLS. 80:109109

Lau, E.S., Zhu, B., Sun, M.A., Ngai, S.M., Ge, W. (2023) Proteomic analysis of zebrafish Folliculogenesis identifies YB-1 (Ybx1/ybx1) as a potential gatekeeping molecule controlling early ovarian Folliculogenesis. Biology of reproduction. 109(4):482-497

Wei, Z., Bagivalu Lakshminarasimha, A., Cone, R., Michel, M. (2023) Loss of Agrp1 in zebrafish: Effects on the growth and reproductive axis. General and comparative endocrinology. 336:114243

Dong, X.R., Wan, S.M., Zhou, J.J., Nie, C.H., Chen, Y.L., Diao, J.H., Gao, Z.X. (2022) Functional Differentiation of BMP7 Genes in Zebrafish: bmp7a for Dorsal-Ventral Pattern and bmp7b for Melanin Synthesis and Eye Development. Frontiers in cell and developmental biology. 10:838721

Hui, S.P., Sugimoto, K., Sheng, D.Z., Kikuchi, K. (2022) Regulatory T cells regulate blastemal proliferation during zebrafish caudal fin regeneration. Frontiers in immunology. 13:981000

Kasica, N., Święch, A., Saładziak, K., Mackiewicz, J., Osęka, M. (2022) The Inhibitory Effect of Selected D₂ Dopaminergic Receptor Agonists on VEGF-Dependent Neovascularization in Zebrafish Larvae: Potential New Therapy in Ophthalmic Diseases. Cells. 11(7):

Rajeswari, J.J., Vélez, E.J., Unniappan, S. (2022) Liver and muscle-specific effects of phoenixin-20 on the insulin-like growth factor system mRNAs in zebrafish. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 63:101456

Weiss, J.M., Hunter, M.V., Cruz, N.M., Baggiolini, A., Tagore, M., Ma, Y., Misale, S., Marasco, M., Simon-Vermot, T., Campbell, N.R., Newell, F., Wilmott, J.S., Johansson, P.A., Thompson, J.F., Long, G.V., Pearson, J.V., Mann, G.J., Scolyer, R.A., Waddell, N., Montal, E.D., Huang, T.H., Jonsson, P., Donoghue, M.T.A., Harris, C.C., Taylor, B.S., Xu, T., Chaligné, R., Shliaha, P.V., Hendrickson, R., Jungbluth, A.A., Lezcano, C., Koche, R., Studer, L., Ariyan, C.E., Solit, D.B., Wolchok, J.D., Merghoub, T., Rosen, N., Hayward, N.K., White, R.M. (2022) Anatomic position determines oncogenic specificity in melanoma. Nature. 604(7905):354-361

Zeng, N., Bao, J., Shu, T., Shi, C., Zhai, G., Jin, X., He, J., Lou, Q., Yin, Z. (2022) Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish. Frontiers in endocrinology. 13:879962

Zhao, T., Ye, Z., Liu, Y., Lin, H., Li, S., Zhang, Y. (2022) Mutation of spexin2 promotes feeding, somatic growth, adiposity and insulin resistance in zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 322(5):R454-R465

Hsieh, Y.W., Tsai, Y.W., Lai, H.H., Lai, C.Y., Lin, C.Y., Her, G.M. (2021) Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite and Gains in Energy Reserves and Body Weight in Zebrafish. Biomedicines. 9(8):

Gu, L., Tian, L., Gao, G., Peng, S., Zhang, J., Wu, D., Huang, J., Hua, Q., Lu, T., Zhong, L., Fu, Z., Pan, X., Qian, H., Sun, L. (2020) Inhibitory effects of polystyrene microplastics on caudal fin regeneration in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 266:114664

Knuth, M.M., Mahapatra, D., Jima, D., Wan, D., Hammock, B.D., Law, M., Kullman, S.W. (2020) Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish. Scientific Reports. 10:16032

Trivellin, G., Tirosh, A., Hernández-Ramírez, L.C., Gupta, T., Tsai-Morris, C.H., Faucz, F.R., Burgess, H.A., Feldman, B., Stratakis, C.A. (2020) The X-linked acrogigantism-associated gene gpr101 is a regulator of early embryonic development and growth in zebrafish. Molecular and Cellular Endocrinology. 520:111091

Viganò, L., Casatta, N., Farkas, A., Mascolo, G., Roscioli, C., Stefani, F., Vitelli, M., Olivo, F., Clerici, L., Robles, P., Dellavedova, P. (2020) Embryo/larval toxicity and transcriptional effects in zebrafish (Danio rerio) exposed to endocrine active riverbed sediments. Environmental science and pollution research international. 27(10):10729-10747

Zhou, W., Wang, J., Zhang, J., Peng, C., Li, G., Li, D. (2020) Environmentally relevant concentrations of geosmin affect the development, oxidative stress, apoptosis and endocrine disruption of embryo-larval zebrafish. The Science of the total environment. 735:139373

Li, J., Dedloff, M.R., Stevens, K., Maney, L., Prochaska, M., Hongay, C.F., Wallace, K.N. (2019) A novel group of secretory cells regulates development of the immature intestinal stem cell niche through repression of the main signaling pathways driving proliferation. Developmental Biology. 456(1):47-62

Obermann, J., Wagner, F., Kociaj, A., Zambusi, A., Ninkovic, J., Hauck, S.M., Chapouton, P. (2019) The Surface Proteome of Adult Neural Stem Cells in Zebrafish Unveils Long-Range Cell-Cell Connections and Age-Related Changes in Responsiveness to IGF. Stem Cell Reports. 12(2):258-273

Chen, Y., Tang, H., Wang, L., He, J., Guo, Y., Liu, Y., Liu, X., Lin, H. (2018) Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish.. Frontiers in endocrinology. 9:567

Dallinga, M.G., Yetkin-Arik, B., Kayser, R.P., Vogels, I.M.C., Nowak-Sliwinska, P., Griffioen, A.W., van Noorden, C.J.F., Klaassen, I., Schlingemann, R.O. (2018) IGF2 and IGF1R identified as novel tip cell genes in primary microvascular endothelial cell monolayers. Angiogenesis. 21:823-836

Dang, Y., Wang, F., Liu, C. (2018) Real-time PCR array to study the effects of chemicals on the growth hormone/insulin-like growth factors (GH/IGFs) axis of zebrafish embryos/larvae. Chemosphere. 207:365-376

de Castro Assis, L.H., Nobrega, R.H., Gómez-González, N.E., Bogerd, J., Schulz, R. (2018) Estrogen-induced inhibition of spermatogenesis in zebrafish is largely reversed by androgen. Journal of molecular endocrinology. 60(4):273-284

Huang, P., Xiong, S., Kang, J., Mei, J., Gui, J.F. (2018) Stat5b Regulates Sexually Dimorphic Gene Expression in Zebrafish Liver.. Frontiers in Physiology. 9:676

Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations. Chemosphere. 218:449-457

Ivanova, A.S., Korotkova, D.D., Ermakova, G.V., Martynova, N.Y., Zaraisky, A.G., Tereshina, M.B. (2018) Ras-dva small GTPases lost during evolution of amniotes regulate regeneration in anamniotes. Scientific Reports. 8:13035

Li, J., Niu, C., Cheng, C.H.K. (2018) Igf3 serves as a mediator of LH in zebrafish ovulation. Biology of reproduction. 99(6):1235-1243

Liu, C., Xin, Y., Bai, Y., Lewin, G., He, G., Mai, K., Duan, C. (2018) Ca²⁺ concentration-dependent premature death of igfbp5a^-/- fish reveals a critical role of IGF signaling in adaptive epithelial growth.. Science signaling. 11(548):

Sun, L., Gu, L., Tan, H., Liu, P., Gao, G., Tian, L., Chen, H., Lu, T., Qian, H., Fu, Z., Pan, X. (2018) Effects of 17α‑ethinylestradiol on caudal fin regeneration in zebrafish larvae. The Science of the total environment. 653:10-22

Takayama, K., Muto, A., Kikuchi, Y. (2018) Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration. Scientific Reports. 8:8278

Zeng, X., Sun, H., Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Effects of environmentally relevant concentrations of tris (2-butoxyethyl) phosphate on growth and transcription of genes involved in the GH/IGF and HPT axes in zebrafish (Danio rerio). Chemosphere. 212:376-384

Zhang, Y., Li, M., Li, S., Wang, Q., Zhu, G., Su, G., Letcher, R.J., Liu, C. (2018) Exposure to tris(1,3-dichloro-2-propyl) phosphate for Two generations decreases fecundity of zebrafish at environmentally relevant concentrations. Aquatic toxicology (Amsterdam, Netherlands). 200:178-187

Zimmerman, M.W., Liu, Y., He, S., Durbin, A.D., Abraham, B.J., Easton, J., Shao, Y., Xu, B., Zhu, S., Zhang, X., Li, Z., Weichert-Leahey, N., Young, R.A., Zhang, J., Look, A.T. (2018) MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer discovery. 8:320-335

Fei, F., Sun, S.Y., Yao, Y.X., Wang, X. (2017) [Generation and phenotype analysis of zebrafish mutations of obesity-related genes lepr and mc4r]. Sheng li xue bao : [Acta physiologica Sinica]. 69:61-69

Hou, J., Su, Y., Lin, W., Guo, H., Xie, P., Chen, J., Gu, Z., Li, L. (2017) Microcystin-LR retards gonadal maturation through disrupting the growth hormone/insulin-like growth factors system in zebrafish. Ecotoxicology and environmental safety. 139:27-35

Hui, S.P., Sheng, D.Z., Sugimoto, K., Gonzalez-Rajal, A., Nakagawa, S., Hesselson, D., Kikuchi, K. (2017) Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs. Developmental Cell. 43:659-672.e5

Liu, Y., Wu, D., Xu, Q., Yu, L., Liu, C., Wang, J. (2017) Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 191:17-24

Sugimoto, K., Hui, S.P., Sheng, D.Z., Kikuchi, K. (2017) Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switch.. eLIFE. 6

Teng, M., Qi, S., Zhu, W., Wang, Y., Wang, D., Yang, Y., Li, H., Li, C., Dong, K., Wang, C. (2017) Sex-specific effects of difenoconazole on the growth hormone endocrine axis in adult zebrafish (Danio rerio). Ecotoxicology and environmental safety. 144:402-408

Yuan, Y., Hong, Y. (2017) Medaka insulin-like growth factor-2 supports self-renewal of the embryonic stem cell line and blastomeres in vitro. Scientific Reports. 7:78

Zhu, Y., Su, G., Yang, D., Zhang, Y., Yu, L., Li, Y., Giesy, J.P., Letcher, R.J., Liu, C. (2017) Time-dependent inhibitory effects of Tris(1, 3-dichloro-2-propyl) phosphate on growth and transcription of genes involved in the GH/IGF axis, but not the HPT axis, in female zebrafish. Environmental pollution (Barking, Essex : 1987). 229:470-478

Baker, B.B., Yee, J.S., Meyer, D.N., Yang, D., Baker, T.R. (2016) Histological and Transcriptomic Changes in Male Zebrafish Testes Due to Early Life Exposure to Low Level 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. Zebrafish. 13:413-423

Bugel, S.M., Wehmas, L.C., La Du, J.K., Tanguay, R.L. (2016) Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. Toxicology and applied pharmacology. 296:31-41

Das, D., Pal, S., Maitra, S. (2016) Releasing prophase arrest in zebrafish oocyte: Synergism between maturational steroid and Igf1. Reproduction (Cambridge, England). 151(1):59-72

Felix Nornberg, B., Azevedo Figueiredo, M., Fernando Marins, L. (2016) Expression profile of IGF paralog genes in liver and muscle of a GH-transgenic zebrafish. General and comparative endocrinology. 226:36-41

Lu, J., Liu, K.C., Schulz, N., Karampelias, C., Charbord, J., Hilding, A., Rautio, L., Bertolino, P., Östenson, C.G., Brismar, K., Andersson, O. (2016) IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation. The EMBO journal. 35(18):2026-44

Nornberg, B.F., Almeida, D.V., Figueiredo, M.A., Marins, L.F. (2016) GH indirectly enhances the regeneration of transgenic zebrafish fins through IGF2a and IGF2b. Transgenic Research. 25(5):743-9

Song, F., Wang, L., Zhu, W., Fu, J., Dong, J., Dong, Z. (2016) A Novel igf3 Gene in Common Carp (Cyprinus carpio): Evidence for Its Role in Regulating Gonadal Development. PLoS One. 11:e0168874

Wirbisky, S.E., Sepúlveda, M.S., Weber, G.J., Jannasch, A.S., Horzmann, K.A., Freeman, J.L. (2016) Embryonic atrazine exposure elicits alterations in genes associated with neuroendocrine function in adult male zebrafish. Toxicological sciences : an official journal of the Society of Toxicology. 153(1):149-64

Wu, C.C., Kruse, F., Vasudevarao, M.D., Junker, J.P., Zebrowski, D.C., Fischer, K., Noël, E.S., Grün, D., Berezikov, E., Engel, F.B., van Oudenaarden, A., Weidinger, G., Bakkers, J. (2016) Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Developmental Cell. 36(1):36-49

Zhou, R., Yu, S.M., Ge, W. (2016) Expression and Functional Characterization of Intrafollicular GH-IGF System in the Zebrafish Ovary. General and comparative endocrinology. 232:32-42

Blum, N., Begemann, G. (2015) Osteoblast de- and redifferentiation is controlled by a dynamic response to retinoic acid during zebrafish fin regeneration. Development (Cambridge, England). 142(17):2894-903

Ivanova, A.S., Shandarin, I.N., Ermakova, G.V., Minin, A.A., Tereshina, M.B., Zaraisky, A.G. (2015) The secreted factor Ag1 missing in higher vertebrates regulates fins regeneration in Danio rerio. Scientific Reports. 5:8123

Li, J., Chu, L., Sun, X., Liu, Y., Cheng, C.H. (2015) Igfs mediate the action of luteinizing hormone on oocyte maturation in zebrafish. Molecular endocrinology (Baltimore, Md.). 29(3):373-83

Lin, J.N., Chang, L.L., Lai, C.H., Lin, K.J., Lin, M.F., Yang, C.H., Lin, H.H., Chen, Y.H. (2015) Development of an Animal Model for Alcoholic Liver Disease in Zebrafish. Zebrafish. 12(4):271-80

Nóbrega, R.H., de Souza Morais, R.D., Crespo, D., de Waal, P.P., de França, L.R., Schulz, R.W., Bogerd, J. (2015) Fsh stimulates spermatogonial proliferation and differentiation in zebrafish via Igf3. Endocrinology. 156(10):3804-17

Schall, K.A., Holoyda, K.A., Grant, C.N., Levin, D.E., Torres, E.R., Maxwell, A., Pollack, H.A., Moats, R.A., Frey, M.R., Darehzereshki, A., Al Alam, D., Lien, C.E., Grikscheit, T.C. (2015) Adult zebrafish intestine resection: a novel model of Short Bowel Syndrome, adaptation, and intestinal stem cell regeneration. American journal of physiology. Gastrointestinal and liver physiology. 309(3):G135-45

Zhu, Y., Ma, X., Su, G., Yu, L., Letcher, R.J., Hou, J., Yu, H., Giesy, J.P., Liu, C. (2015) Environmentally Relevant Concentrations of the Flame Retardant Tris(1,3-dichloro-2-propyl) Phosphate (TDCIPP) Inhibits Growth of Female Zebrafish and Decreases Fecundity. Environmental science & technology. 49(24):14579-87

Li, J., Wu, P., Liu, Y., Wang, D., Cheng, C.H. (2014) Temporal and Spatial Expression of the four Igf Ligands and two Igf Type 1 Receptors in Zebrafish during Early Embryonic Development. Gene expression patterns : GEP. 15(2):104-11

Wehner, D., Cizelsky, W., Vasudevaro, M.D., Özhan, G., Haase, C., Kagermeier-Schenk, B., Röder, A., Dorsky, R.I., Moro, E., Argenton, F., Kühl, M., and Weidinger, G. (2014) Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin. Cell Reports. 6(3):467-481

Choi, W.Y., Gemberling, M., Wang, J., Holdway, J.E., Shen, M.C., Karlstrom, R.O., and Poss, K.D. (2013) In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration. Development (Cambridge, England). 140(3):660-666

Gauron, C., Rampon, C., Bouzaffour, M., Ipendey, E., Teillon, J., Volovitch, M., and Vriz, S. (2013) Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed. Scientific Reports. 3:2084

Huang, Y., Harrison, M.R., Osorio, A., Kim, J., Baugh, A., Duan, C., Sucov, H.M., and Lien, C.L. (2013) Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration. PLoS One. 8(6):e67266

McMenamin, S.K., Minchin, J.E., Gordon, T.N., Rawls, J.F., and Parichy, D.M. (2013) Dwarfism and Increased Adiposity in the gh1 Mutant Zebrafish vizzini. Endocrinology. 154(4):1476-87

Blum, N., and Begemann, G. (2012) Retinoic acid signaling controls the formation, proliferation and survival of the blastema during adult zebrafish fin regeneration. Development (Cambridge, England). 139(1):107-16

Irwin, D.A., and Van Der Kraak, G. (2012) Regulation and actions of insulin-like growth factors in the ovary of zebrafish (Danio rerio). General and comparative endocrinology. 177(1):187-194

Nesan, D., Kamkar, M., Burrows, J., Scott, I.C., Marsden, M., Vijayan, M.M. (2012) Glucocorticoid Receptor Signaling Is Essential for Mesoderm Formation and Muscle Development in Zebrafish. Endocrinology. 153(3):1288-1300

Amaral, I.P., and Johnston, I.A. (2011) Insulin-like growth factor (IGF) signalling and genome-wide transcriptional regulation in fast muscle of zebrafish following a single-satiating meal. The Journal of experimental biology. 214(13):2125-2139

Kamei, H., Ding, Y., Kajimura, S., Wells, M., Chiang, P., and Duan, C. (2011) Role of IGF signaling in catch-up growth and accelerated temporal development in zebrafish embryos in response to oxygen availability. Development (Cambridge, England). 138(4):777-786

Yuan, X.N., Jiang, X.Y., Pu, J.W., Li, Z.R., and Zou, S.M. (2011) Functional conservation and divergence of duplicated insulin-like growth factor 2 genes in grass carp (Ctenopharyngodon idellus). Gene. 470(1-2):46-52

Chablais, F., and Jazwinska, A. (2010) IGF signaling between blastema and wound epidermis is required for fin regeneration. Development (Cambridge, England). 137(6):871-879

Hartnett, L., Glynn, C., Nolan, C.M., Grealy, M., and Byrnes, L. (2010) Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos. The International journal of developmental biology. 54(4):573-583

Nelson, S.N., and Van Der Kraak, G. (2010) Characterization and regulation of the insulin-like growth factor (IGF) system in the zebrafish (Danio rerio) ovary. General and comparative endocrinology. 168(1):111-120

Wan, G., and Chan, K.M. (2010) A study of somatolactin actions by ectopic expression in transgenic zebrafish larvae. Journal of molecular endocrinology. 45(5):301-315

Wang, H. (2009) Comparative genomic analysis of teleost fish bmal genes. Genetica. 136(1):149-161

White, Y.A., Kyle, J.T., and Wood, A.W. (2009) Targeted Gene Knockdown in Zebrafish Reveals Distinct Intraembryonic Functions for Insulin-Like Growth Factor II Signaling. Endocrinology. 150(9):4366-4375

Zou, S., Kamei, H., Modi, Z., and Duan, C. (2009) Zebrafish IGF genes: gene duplication, conservation and divergence, and novel roles in midline and notochord development. PLoS One. 4(9):e7026

Hegde, A., Qiu, N.C., Qiu, X., Ho, S.H., Tay, K.Q., George, J., Ng, F.S., Govindarajan, K.R., Gong, Z., Mathavan, S., and Jiang, Y.J. (2008) Genomewide Expression Analysis in Zebrafish mind bomb Alleles with Pancreas Defects of Different Severity Identifies Putative Notch Responsive Genes. PLoS One. 3(1):e1479

Rekha, R.D., Amali, A.A., Her, G.M., Yeh, Y.H., Gong, H.Y., Hu, S.Y., Lin, G.H., and Wu, J.L. (2008) Thioacetamide accelerates steatohepatitis, cirrhosis and HCC by expressing HCV core protein in transgenic zebrafish Danio rerio. Toxicology. 243(1-2):11-22

Sang, X., Curran, M.S., and Wood, A.W. (2008) Paracrine insulin-like growth factor signaling influences primordial germ cell migration: in vivo evidence from the zebrafish model. Endocrinology. 149(10):5035-5042

Kohn, M., Hogel, J., Vogel, W., Minich, P., Kehrer-Sawatzki, H., Graves, J.A., and Hameister, H. (2006) Reconstruction of a 450-My-old ancestral vertebrate protokaryotype. Trends in genetics : TIG. 22(4):203-210

Lien, C.L., Schebesta, M., Makino, S., Weber, G.J., and Keating, M.T. (2006) Gene Expression Analysis of Zebrafish Heart Regeneration. PLoS Biology. 4(8):e260

Additional Citations (24):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

Zebrafish Nomenclature Committee (2017) Nomenclature Data Curation (2017). Nomenclature Committee Submission.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2016) Automated addition of links from ZFIN gene pages to SignaFish. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.