ZFIN

ZFIN ID: ZDB-GENE-980526-326

ZFIN ID: ZDB-GENE-980526-326

CITATIONS (291 total)

Gene Name:	fms related receptor tyrosine kinase 4
Gene Symbol:	flt4

Gafranek, J.T., D'Aniello, E., Ravisankar, P., Thakkar, K., Vagnozzi, R.J., Lim, H.W., Salomonis, N., Waxman, J.S. (2023) Sinus venosus adaptation models prolonged cardiovascular disease and reveals insights into evolutionary transitions of the vertebrate heart. Nature communications. 14:55095509

Capon, S.J., Uribe, V., Dominado, N., Ehrlich, O., Smith, K.A. (2022) Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2. Development (Cambridge, England). 149(9):

Das, R.N., Tevet, Y., Safriel, S., Han, Y., Moshe, N., Lambiase, G., Bassi, I., Nicenboim, J., Brückner, M., Hirsch, D., Eilam-Altstadter, R., Herzog, W., Avraham, R., Poss, K.D., Yaniv, K. (2022) Generation of specialized blood vessels via lymphatic transdifferentiation. Nature. 606(7914):570-575

El-Sammak, H., Yang, B., Guenther, S., Chen, W., Marín-Juez, R., Stainier, D.Y.R. (2022) A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. Circulation research. 130(7):1014-1029

Green, L.A., O'Dea, M.R., Hoover, C.A., DeSantis, D.F., Smith, C.J. (2022) The embryonic zebrafish brain is seeded by a lymphatic-dependent population of mrc1⁺ microglia precursors. Nature Neuroscience. 25(7):849-864

Lange, M., Ohnesorge, N., Hoffmann, D., Rocha, S.F., Benedito, R., Siekmann, A.F. (2022) Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling. Developmental Biology. 486:26-43

Li, R.F., Wang, Y.S., Lu, F.I., Huang, Y.S., Chiu, C.C., Tai, M.H., Wu, C.Y. (2022) Identification of Novel Vascular Genes Downstream of Islet2 and Nr2f1b Transcription Factors. Biomedicines. 10(6)

Lo, Y.H., Huang, Y.S., Chang, Y.C., Hung, P.Y., Wang, W.D., Liu, W., Urade, R., Wen, Z.H., Wu, C.Y. (2022) GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development. Biomedicines. 10(12):

Peng, D., Ando, K., Hußmann, M., Gloger, M., Skoczylas, R., Mochizuki, N., Betsholtz, C., Fukuhara, S., Schulte-Merker, S., Lawson, N.D., Koltowska, K. (2022) Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells. eLIFE. 11

Wang, Y.S., Huang, Y.S., Chiu, C.C., Wu, T.Y., Zhou, J.Q., Liang, S.R., Tai, M.H., Wu, C.Y. (2022) Interaction of transcription factors Islet2 and Nr2f1b to control vascular patterning during zebrafish development. Biochemical and Biophysical Research Communications. 604:123-129

Wu, M., Chen, Q., Li, J., Xu, Y., Lian, J., Liu, Y., Meng, P., Zhang, Y. (2022) Gfi1aa/Lsd1 Facilitates Hemangioblast Differentiation Into Primitive Erythrocytes by Targeting etv2 and sox7 in Zebrafish. Frontiers in cell and developmental biology. 9:786426

An, G., Park, H., Lim, W., Song, G. (2021) Fluroxypyr-1-methylheptyl ester interferes with the normal embryogenesis of zebrafish by inducing apoptosis, inflammation, and neurovascular toxicity. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 247:109069

Dong, W., Han, X., Bao, C., Tai, S., Bai, Y., Xu, L., Yang, J., Leung, T., Ao, W., Dong, W. (2021) Inhibitory Effects of Euphorbia ebracteolata Hayata Extract ECB on Melanoma-Induced Hyperplasia of Blood Vessels in Zebrafish Embryos. Evidence-based complementary and alternative medicine : eCAM. 2021:5543259

Fowler, G., French, D., Rose, A., Squires, P., Anecito da Silva, C., Ohata, S., Okamoto, H., French, C.R. (2021) Protein fucosylation is required for Notch dependent vascular integrity in zebrafish. Developmental Biology. 480:62-68

Hu, M., Liu, P., Lu, S., Wang, Z., Lyu, Z., Liu, H., Sun, Y., Liu, F., Tian, J. (2021) Myocardial protective effect and transcriptome profiling of Naoxintong on cardiomyopathy in zebrafish. Chinese Medicine. 16:119

Jerafi-Vider, A., Bassi, I., Moshe, N., Tevet, Y., Hen, G., Splittstoesser, D., Shin, M., Lawson, N.D., Yaniv, K. (2021) VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells. Cell Reports. 35:109255

Lee, J.Y., Park, H., Lim, W., Song, G. (2021) Benfuresate induces developmental toxicity in zebrafish larvae by generating apoptosis and pathological modifications. Pesticide biochemistry and physiology. 172:104751

Lee, J.Y., Park, H., Lim, W., Song, G. (2021) Aclonifen causes developmental abnormalities in zebrafish embryos through mitochondrial dysfunction and oxidative stress. The Science of the total environment. 771:145445

Lee, J.Y., Park, S., Lim, W., Song, G. (2021) Picolinafen exerts developmental toxicity via the suppression of oxidative stress and angiogenesis in zebrafish embryos. Pesticide biochemistry and physiology. 171:104734

Lei, D., Zhang, X., Rouf, M.A., Mahendra, Y., Wen, L., Li, Y., Zhang, X., Li, L., Wang, L., Zhang, T., Wang, G., Wang, Y. (2021) Noncanonical protease-activated receptor 1 regulates lymphatic differentiation in zebrafish. iScience. 24:103386

Mauri, C., van Impel, A., Mackay, E.W., Schulte-Merker, S. (2021) The adaptor protein Grb2b is an essential modulator for lympho-venous sprout formation in the zebrafish trunk. Angiogenesis. 24(2):345-362

Metikala, S., Casie Chetty, S., Sumanas, S. (2021) Single-cell transcriptome analysis of the zebrafish embryonic trunk. PLoS One. 16:e0254024

Okuda, K.S., Ng, M.F., Ruslan, N.F., Bower, N.I., Song, D.S.S., Chen, H., Baek, S., Crosier, P.S., Koltowska, K., Astin, J.W., Tan, P.J., Hogan, B.M., Patel, V. (2021) 3,4-Difluorobenzocurcumin Inhibits Vegfc-Vegfr3-Erk Signalling to Block Developmental Lymphangiogenesis in Zebrafish. Pharmaceuticals (Basel, Switzerland). 14(7):

Parab, S., Quick, R.E., Matsuoka, R.L. (2021) Endothelial cell type-specific molecular requirements for angiogenesis drive fenestrated vessel development in the brain. eLIFE. 10:

Perens, E.A., Diaz, J.T., Quesnel, A., Askary, A., Crump, J.G., Yelon, D. (2021) osr1 couples intermediate mesoderm cell fate with temporal dynamics of vessel progenitor cell differentiation. Development (Cambridge, England). 148(15):

Postlethwait, J.H., Massaquoi, M.S., Farnsworth, D.R., Yan, Y.L., Guillemin, K., Miller, A.C. (2021) The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafish. Biology Open. 10(3):

Wang, K., Xu, Q., Zhong, H. (2021) The Bruton's Tyrosine Kinase Inhibitor Ibrutinib Impairs the Vascular Development of Zebrafish Larvae. Frontiers in pharmacology. 11:625498

Bae, H., Lee, J.Y., Yang, C., Song, G., Lim, W. (2020) Fucoidan Derived from Fucus vesiculosus Inhibits the Development of Human Ovarian Cancer via the Disturbance of Calcium Homeostasis, Endoplasmic Reticulum Stress, and Angiogenesis. Marine drugs. 18(1):

Chestnut, B., Casie Chetty, S., Koenig, A.L., Sumanas, S. (2020) Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle. Nature communications. 11:2796

Cohen, B., Tempelhof, H., Raz, T., Oren, R., Nicenboim, J., Bochner, F., Even, R., Jelinski, A., Eilam, R., Ben-Dor, S., Adaddi, Y., Golani, O., Lazar, S., Yaniv, K., Neeman, M. (2020) BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression. Life science alliance. 3(4):

Dobrzycki, T., Mahony, C.B., Krecsmarik, M., Koyunlar, C., Rispoli, R., Peulen-Zink, J., Gussinklo, K., Fedlaoui, B., de Pater, E., Patient, R., Monteiro, R. (2020) Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis. Communications biology. 3:71

Espanola, S.G., Song, H., Ryu, E., Saxena, A., Kim, E.S., Manegold, J.E., Nasamran, C.A., Sahoo, D., Oh, C.K., Bickers, C., Shin, U., Grainger, S., Park, Y.H., Pandolfo, L., Kang, M.S., Kang, S., Myung, K., Cooper, K.L., Yelon, D., Traver, D., Lee, Y. (2020) Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nature cell biology. 22(12):1411-1422

Fontana, F., Haack, T., Reichenbach, M., Knaus, P., Puceat, M., Abdelilah-Seyfried, S. (2020) Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis. Cell Reports. 32:107883

Guo, Y., Cheng, B.Y.L., Wang, D., Ma, A.C.H., He, B.L., Man, T.K., Cheung, M.P.L., Shi, X., Ng, N.K.L., Leung, A.Y.H. (2020) Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium. Stem Cell Reports. 14(4):575-589

Huang, J., Sun, L., Mennigen, J.A., Liu, Y., Liu, S., Zhang, M., Wang, Q., Tu, W. (2020) Developmental toxicity of the novel PFOS alternative OBS in developing zebrafish: An emphasis on cilia disruption. Journal of hazardous materials. 409:124491

Klems, A., van Rijssel, J., Ramms, A.S., Wild, R., Hammer, J., Merkel, M., Derenbach, L., Préau, L., Hinkel, R., Suarez-Martinez, I., Schulte-Merker, S., Vidal, R., Sauer, S., Kivelä, R., Alitalo, K., Kupatt, C., van Buul, J.D., le Noble, F. (2020) The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Nature communications. 11:5319

Lee, J.Y., Bae, H., Yang, C., Park, S., Youn, B.S., Kim, H.S., Song, G., Lim, W. (2020) Eupatilin Promotes Cell Death by Calcium Influx through ER-Mitochondria Axis with SERPINB11 Inhibition in Epithelial Ovarian Cancer. Cancers. 12(6):

Lee, J.Y., Park, S., Lim, W., Song, G. (2020) Orbencarb induces lethality and organ malformation in zebrafish embryos during development. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 233:108771

Li, G.X., Zhang, S., Liu, R., Singh, B., Singh, S., Quinn, D.I., Crump, G., Gill, P.S. (2020) Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways. Biology Open. 10(2):

Lu, S., Hu, M., Wang, Z., Liu, H., Kou, Y., Lyu, Z., Tian, J. (2020) Generation and Application of the Zebrafish heg1 Mutant as a Cardiovascular Disease Model. Biomolecules. 10(11):

Lv, H., Liu, B., Qin, Y. (2020) Isosorbide mononitrate promotes angiogenesis in embryonic development of zebrafish. Genetics and Molecular Biology. 43:20190233

Medrano, M.P., Pisera-Fuster, A., Bernabeu, R.O., Faillace, M.P. (2020) P2X7 and A_2A receptor endogenous activation protects against neuronal death caused by CoCl₂ -induced photoreceptor toxicity in the zebrafish retina. The Journal of comparative neurology. 528(12):2000-2020

Park, S., Lee, J.Y., Park, H., Song, G., Lim, W. (2020) Haloxyfop-P-methyl induces developmental defects in zebrafish embryos through oxidative stress and anti-vasculogenesis. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 233:108761

Weaver, M.L., Piedade, W.P., Meshram, N.N., Famulski, J.K. (2020) Hyaloid vasculature and mmp2 activity play a role during optic fissure fusion in zebrafish. Scientific Reports. 10:10136

Baek, S., Oh, T.G., Secker, G., Sutton, D.L., Okuda, K.S., Paterson, S., Bower, N.I., Toubia, J., Koltowska, K., Capon, S.J., Baillie, G.J., Simons, C., Muscat, G.E.O., Lagendijk, A.K., Smith, K.A., Harvey, N.L., Hogan, B.M. (2019) The Alternative Splicing Regulator Nova2 Constrains Vascular Erk Signaling to Limit Specification of the Lymphatic Lineage. Developmental Cell. 49:279-292.e5

Ferri-Lagneau, K.F., Haider, J., Sang, S., Leung, T. (2019) Rescue of hematopoietic stem/progenitor cells formation in plcg1 zebrafish mutant. Scientific Reports. 9:244

Gancz, D., Raftrey, B.C., Perlmoter, G., Marín-Juez, R., Semo, J., Matsuoka, R.L., Karra, R., Raviv, H., Moshe, N., Addadi, Y., Golani, O., Poss, K.D., Red-Horse, K., Stainier, D.Y., Yaniv, K. (2019) Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration. eLIFE. 8:

Harrison, M.R., Feng, X., Mo, G., Aguayo, A., Villafuerte, J., Yoshida, T., Pearson, C.A., Schulte-Merker, S., Lien, C.L. (2019) Late developing cardiac lymphatic vasculature supports adult zebrafish heart function and regeneration. eLIFE. 8:

Iwasaki, R., Tsuge, K., Kishimoto, K., Hayashi, Y., Iwaana, T., Hohjoh, H., Inazumi, T., Kawahara, A., Tsuchiya, S., Sugimoto, Y. (2019) Essential role of prostaglandin E₂ and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis. Scientific Reports. 9:7650

Kobayashi, I., Kobayashi-Sun, J., Hirakawa, Y., Ouchi, M., Yasuda, K., Kamei, H., Fukuhara, S., Yamaguchi, M. (2019) Dual role of Jam3b in early hematopoietic and vascular development. Development (Cambridge, England). 147(1):

Liu, Z., Tu, H., Kang, Y., Xue, Y., Ma, D., Zhao, C., Li, H., Wang, L., Liu, F. (2019) Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish. Nature communications. 10:1839

Lu, F.I., Wang, Y.T., Wang, Y.S., Wu, C.Y., Li, C.C. (2019) Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(9):9959-9973

Mullapudi, S.T., Boezio, G.L.M., Rossi, A., Marass, M., Matsuoka, R.L., Matsuda, H., Helker, C.S.M., Yang, Y.H.C., Stainier, D.Y.R. (2019) Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function. Development (Cambridge, England). 146(21):

Page, D.J., Thuret, R., Venkatraman, L., Takahashi, T., Bentley, K., Herbert, S.P. (2019) Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis. Cell Reports. 27:3139-3151.e5

Park, H., Lee, J.Y., Park, S., Song, G., Lim, W. (2019) Developmental toxicity and angiogenic defects of etoxazole exposed zebrafish (Danio rerio) larvae. Aquatic toxicology (Amsterdam, Netherlands). 217:105324

Park, H., Lee, J.Y., Park, S., Song, G., Lim, W. (2019) Developmental toxicity of fipronil in early development of zebrafish (Danio rerio) larvae: Disrupted vascular formation with angiogenic failure and inhibited neurogenesis. Journal of hazardous materials. 385:121531

Park, M.H., Kim, A.K., Manandhar, S., Oh, S.Y., Jang, G.H., Kang, L., Lee, D.W., Hyeon, D.Y., Lee, S.H., Lee, H.E., Huh, T.L., Suh, S.H., Hwang, D., Byun, K., Park, H.C., Lee, Y.M. (2019) CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity. eLIFE. 8:

Park, S., Lee, J.Y., Park, H., Song, G., Lim, W. (2019) Toxic effects of flufenoxuron on development and vascular formation during zebrafish embryogenesis. Aquatic toxicology (Amsterdam, Netherlands). 216:105307

Park, S., Lee, J.Y., Park, H., Song, G., Lim, W. (2019) Bifenthrin induces developmental immunotoxicity and vascular malformation during zebrafish embryogenesis. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 228:108671

Pociute, K., Schumacher, J.A., Sumanas, S. (2019) Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish. BMC Developmental Biology. 19:6

Rho, S.S., Kobayashi, I., Oguri-Nakamura, E., Ando, K., Fujiwara, M., Kamimura, N., Hirata, H., Iida, A., Iwai, Y., Mochizuki, N., Fukuhara, S. (2019) Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Developmental Cell. 49(5):681-696.e6

Saito, E., Isogai, S., Deguchi, T., Ishida, K., Nozaki, T., Ishiyama, E., Wayama, M., Shimoda, H. (2019) Intraperitoneal dye injection method for visualizing the functioning lymphatic vascular system in zebrafish and medaka. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(5):679-692

Savage, A.M., Kurusamy, S., Chen, Y., Jiang, Z., Chhabria, K., MacDonald, R.B., Kim, H.R., Wilson, H.L., van Eeden, F.J.M., Armesilla, A.L., Chico, T.J.A., Wilkinson, R.N. (2019) tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis. Nature communications. 10:732

Tian, L., Sheng, D., Li, Q., Guo, C., Zhu, G. (2019) Preliminary safety assessment of oridonin in zebrafish. Pharmaceutical biology. 57:632-640

Tobia, C., Chiodelli, P., Barbieri, A., Buraschi, S., Ferrari, E., Mitola, S., Borsani, G., Guerra, J., Presta, M. (2019) Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migration. Frontiers in immunology. 10:1092

Vivien, C.J., Pichol-Thievend, C., Sim, C.B., Smith, J.B., Bower, N.I., Hogan, B.M., Hudson, J.E., Francois, M., Porrello, E.R. (2019) Vegfc/d-dependent regulation of the lymphatic vasculature during cardiac regeneration is influenced by injury context. NPJ Regenerative medicine. 4:18

Vogrin, A.J., Bower, N.I., Gunzburg, M.J., Roufail, S., Okuda, K.S., Paterson, S., Headey, S.J., Stacker, S.A., Hogan, B.M., Achen, M.G. (2019) Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis. Cell Reports. 28:2023-2036.e4

Xue, Y., Liu, D., Cui, G., Ding, Y., Ai, D., Gao, S., Zhang, Y., Suo, S., Wang, X., Lv, P., Zhou, C., Li, Y., Chen, X., Peng, G., Jing, N., Han, J.J., Liu, F. (2019) A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis. Cell Reports. 27:1567-1578.e5

Zhang, D., Zhou, F., Zhao, X., Liu, B., Chen, J., Yang, J. (2019) Endoglin is a conserved regulator of vasculogenesis in zebrafish-Implications for hereditary haemorrhagic telangiectasia. Bioscience Reports. 39(5):

Carra, S., Sangiorgio, L., Pelucchi, P., Cermenati, S., Mezzelani, A., Martino, V., Palizban, M., Albertini, A., Götte, M., Kehler, J., Deflorian, G., Beltrame, M., Giordano, A., Reinbold, R., Cotelli, F., Bellipanni, G., Zucchi, I. (2018) Zebrafish Tmem230a cooperates with the Delta/Notch signaling pathway to modulate endothelial cell number in angiogenic vessels. Journal of Cellular Physiology. 233(2):1455-1467

Davis, J.A., Koenig, A.L., Lubert, A., Chestnut, B., Liu, F., Desai, S.P., Winkler, T., Pociute, K., Choi, K., Sumanas, S. (2018) ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression. Developmental Biology. 440(1):40-52

Gauvrit, S., Villasenor, A., Strilic, B., Kitchen, P., Collins, M.M., Marín-Juez, R., Guenther, S., Maischein, H.M., Fukuda, N., Canham, M.A., Brickman, J.M., Bogue, C.W., Jayaraman, P.S., Stainier, D.Y.R. (2018) HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development. Nature communications. 9:2704

Huang, C.X., Huang, Y., Duan, X.K., Zhang, M., Tu, J.P., Liu, J.X., Liu, H., Chen, T.S., Wang, W.M., Wang, H.L. (2018) Zebrafish miR-462-731 regulates hematopoietic specification and pu.1-dependent primitive myelopoiesis. Cell death and differentiation. 26(8):1531-1544

Kontarakis, Z., Rossi, A., Ramas, S., Dellinger, M.T., Stainier, D.Y.R. (2018) Mir-126 is a conserved modulator of lymphatic development. Developmental Biology. 437(2):120-130

Mahony, C.B., Pasche, C., Bertrand, J.Y. (2018) Oncostatin M and Kit-Ligand Control Hematopoietic Stem Cell Fate during Zebrafish Embryogenesis. Stem Cell Reports. 10(6):1920-1934

Medrano, M.P., Pisera Fuster, A., Sanchis, P., Paez, N., Bernabeu, R.O., Faillace, M.P. (2018) Characterization of proliferative, glial and angiogenic responses after a CoCl₂ -induced injury of photoreceptor cells in the adult zebrafish retina.. The European journal of neuroscience. 48(9):3019-3042

Nadarajah, N., Schulte, D., McConnell, V., Martin-Almedina, S., Karapouliou, C., Mortimer, P.S., Jeffery, S., Schulte-Merker, S., Gordon, K., Mansour, S., Ostergaard, P. (2018) A Novel Splice-Site Mutation in VEGFC Is Associated with Congenital Primary Lymphoedema of Gordon.. International Journal of Molecular Sciences. 19(8)

Tao, B., Hu, H., Mitchell, K., Chen, J., Jia, H., Zhu, Z., Trudeau, V.L., Hu, W. (2018) Secretogranin-II plays a critical role in zebrafish neurovascular modeling. Journal of molecular cell biology. 10(5):388-401

Wang, X., Li, J., Yang, Z., Wang, L., Li, L., Deng, W., Zhou, J., Wang, L., Xu, C., Chen, Q., Wang, Q.K. (2018) phlda3 overexpression impairs specification of hemangioblasts and vascular development. The FEBS journal. 285(21):4071-4081

Bower, N.I., Koltowska, K., Pichol-Thievend, C., Virshup, I., Paterson, S., Lagendijk, A.K., Wang, W., Lindsey, B.W., Bent, S.J., Baek, S., Rondon-Galeano, M., Hurley, D.G., Mochizuki, N., Simons, C., Francois, M., Wells, C.A., Kaslin, J., Hogan, B.M. (2017) Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish. Nature Neuroscience. 20(6):774-783

Bower, N.I., Vogrin, A.J., Le Guen, L., Chen, H., Stacker, S.A., Achen, M.G., Hogan, B.M. (2017) Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development. Development (Cambridge, England). 144(3):507-518

Chang, H.W., Wang, W.D., Chiu, C.C., Chen, C.H., Wang, Y.S., Chen, Z.Y., Liu, W., Tai, M.H., Wen, Z.H., Wu, C.Y. (2017) Ftr82 Is Critical for Vascular Patterning during Zebrafish Development. International Journal of Molecular Sciences. 18(1)

Chen, X., Gays, D., Milia, C., Santoro, M.M. (2017) Cilia Control Vascular Mural Cell Recruitment in Vertebrates. Cell Reports. 18:1033-1047

Chetty, S.C., Rost, M.S., Enriquez, J.R., Schumacher, J.A., Baltrunaite, K., Rossi, A., Stainier, D.Y., Sumanas, S. (2017) Vegf Signaling Promotes Vascular Endothelial Differentiation by Modulating etv2 Expression. Developmental Biology. 424(2):147-161

De Angelis, J.E., Lagendijk, A.K., Chen, H., Tromp, A., Bower, N.I., Tunny, K.A., Brooks, A.J., Bakkers, J., Francois, M., Yap, A.S., Simons, C., Wicking, C., Hogan, B.M., Smith, K.A. (2017) Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover. Developmental Cell. 40:123-136

Ernens, I., Lumley, A.I., Zhang, L., Devaux, Y., Wagner, D.R. (2017) Hypoxia inhibits lymphatic thoracic duct formation in zebrafish. Biochemical and Biophysical Research Communications. 482(4):1129-1134

Fish, J.E., Cantu Gutierrez, M., Dang, L.T., Khyzha, N., Chen, Z., Veitch, S., Cheng, H.S., Khor, M., Antounians, L., Njock, M.S., Boudreau, E., Herman, A.M., Rhyner, A.M., Ruiz, O.E., Eisenhoffer, G.T., Medina-Rivera, A., Wilson, M.D., Wythe, J.D. (2017) Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network. Development (Cambridge, England). 144:2428-2444

Hashiura, T., Kimura, E., Fujisawa, S., Oikawa, S., Nonaka, S., Kurosaka, D., Hitomi, J. (2017) Live imaging of primary ocular vasculature formation in zebrafish. PLoS One. 12:e0176456

Hu, Z., Liu, Y., Huarng, M.C., Menegatti, M., Reyon, D., Rost, M.S., Norris, Z.G., Richter, C.E., Stapleton, A.N., Chi, N.C., Peyvandi, F., Joung, J.K., Shavit, J.A. (2017) Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway. Blood. 130(5):666-676

Hwangbo, C., Lee, H.W., Kang, H., Ju, H., Wiley, D.S., Papangeli, I., Han, J., Kim, J.D., Dunworth, W.P., Hu, X., Lee, S., El-Hely, O., Sofer, A., Pak, B., Peterson, L., Comhair, S., Hwang, E.M., Park, J.Y., Thomas, J.L., Bautch, V.L., Erzurum, S.C., Chun, H.J., Jin, S.W. (2017) Modulation of Endothelial BMPR2 Activity by VEGFR3 in Pulmonary Arterial Hypertension. Circulation. 135(23):2288-2298

Jin, D., Zhu, D., Fang, Y., Chen, Y., Yu, G., Pan, W., Liu, D., Li, F., Zhong, T.P. (2017) Vegfa signaling regulates diverse artery/vein formation in vertebrate vasculatures. Journal of genetics and genomics = Yi chuan xue bao. 44(10):483-492

Matsuoka, R.L., Rossi, A., Stone, O.A., Stainier, D.Y.R. (2017) CNS-resident progenitors direct the vascularization of neighboring tissues. Proceedings of the National Academy of Sciences of the United States of America. 114(38):10137-10142

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ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. Manually curated data.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

GOA, HGNC, AgBase and UniProtKB curators (2007) Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. ZFIN Direct Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

Thisse, B., Pflumio, S., Fürthauer, M., Loppin, B., Heyer, V., Degrave, A., Woehl, R., Lux, A., Steffan, T., Charbonnier, X.Q. and Thisse, C. (2001) Expression of the zebrafish genome during embryogenesis (NIH R01 RR15402). ZFIN Direct Data Submission.