ZFIN ID: ZDB-TGCONSTRCT-070117-24
Transgenic Construct Name: Tg(5xUAS-E1b:6xMYC-notch1a)
Sequence Ontology ID :
Synonyms: NICD (1), Tg(UAS:myc-Notch1a-intra), UAS-myc-Notch1a:intra (1)

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Note: This construct utilizes five copies of an optimized UAS from yeast and the minimal E1b promoter to drive the expression of a protein in which six myc epitopes are fused to the intracellular domain of the zebrafish notch1a protein.

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CONSTRUCT COMPONENTS
Regulatory Regions: UAS (1)
Coding Sequences: notch1a (1)
Contains: MYC (1)
GENOMIC FEATURES THAT UTILIZE Tg(5xUAS-E1b:6xMYC-notch1a)
Genomic Feature Affected Genomic Regions    
kca3Tg    
TRANSGENICS THAT UTILIZE Tg(5xUAS-E1b:6xMYC-notch1a)
Fish Affected Genomic Regions Phenotype Gene Expression
bw9Tg; kca3Tg Fig. 5 from Kim et al., 2014
cj3Tg; kca3Tg 2 figures from Collins et al., 2010
dctn1as309/s309; kca3Tg; kca4Tg(TL) dctn1a Fig. 6 with image from Del Bene et al., 2008
gt1Tg; jh11Tg; kca3Tg; kca4Tg Fig. S12 from Huang et al., 2014 Fig. S12 from Huang et al., 2014
hdac1hi1618Tg/hi1618Tg; kca3Tg; kca4Tg hdac1 Fig. 5 from Burns et al., 2009 Fig. 5 from Burns et al., 2009
hu4008Tg; kca3Tg; kca4Tg; zf131Tg Fig. 6 with image from Grotek et al., 2013
hu10049Tg; kca3Tg
hzm7Et; kca3Tg Fig. 5 from Kim et al., 2014
kca3Tg 5 figures with image from 4 publications
kca3Tg ; kca4Tg ; um14Tg ; vc6Tg Fig. 5 with image from Samsa et al., 2015
kca3Tg/+
kca3Tg/+(AB)
kca3Tg/+; kca4Tg/+ 9 figures with image from 6 publications 14 figures with image from 9 publications
kca3Tg/+; kca4Tg/+; knu2Tg/+
kca3Tg/+; kca4Tg/+; s939Tg; um14Tg Fig. 6 with image from Delous et al., 2012
kca3Tg/+; kca4Tg/+; sb1Tg/+ Fig. 5 from Kishimoto et al., 2013
kca3Tg/+; kca4Tg/+; y83Tg/+
kca3Tg/+; m1080Tg/+ Fig. 8 with image from Zecchin et al., 2007
kca3Tg/+; m1080Tg/m1080Tg Fig. 8 with image from Zecchin et al., 2007
kca3Tg/+; vu12Tg; vu22Tg Fig. 5 with image from Shin et al., 2007
kca3Tg/kca3Tg; kca4Tg/kca4Tg Fig. 7 with image from Kapsimali et al., 2011 2 figures with image from 2 publications
kca3Tg; kca4Tg 13 figures with image from 11 publications 25 figures with image from 19 publications
kca3Tg; kca4Tg; knu3Tg Fig. 5 with image from Quillien et al., 2011
kca3Tg; kca4Tg; la2Tg; s939Tg Fig. 4 with image from Sawamiphak et al., 2014 Fig. 4 with image from Sawamiphak et al., 2014
kca3Tg; kca4Tg; la781Tg Fig. 2 with image from Lee et al., 2009
kca3Tg; kca4Tg; nl1Tg Fig. 5 from Mizoguchi et al., 2011
kca3Tg; kca4Tg; s843Tg Fig. 1 with image from Lee et al., 2009
kca3Tg; kca4Tg; vu12Tg Fig. 5 with image from Shin et al., 2007
kca3Tg; kca4Tg; x17Tg Fig. 8 with image from Kantarci et al., 2015 Fig. 8 with image from Kantarci et al., 2015
kca3Tg; kca4Tg; y1Tg Fig. 1 from Siekmann et al., 2007
kca3Tg; kca4Tg; y83Tg Fig. 4 with image from Grotek et al., 2013
kca3Tg; mu101Tg; nkuasgfp1aTg Fig. 2 with image from Bussmann et al., 2011 Fig. 2 with image from Bussmann et al., 2011
kca3Tg; nkhspGFF53AEt; nkuasgfp1aTg Fig. 6 with image from Faucherre et al., 2011 Fig. 6 with image from Faucherre et al., 2011
kca3Tg; nns5Tg; nns6Tg Fig. S3 with image from Kimura et al., 2008 Fig. S3 with image from Kimura et al., 2008
kca3Tg; nns6Tg
kca3Tg; pd1023Tg Fig. 7 from Ellis et al., 2013
kca3Tg; s1001tEt; s1999tTg Fig. 6 with image from Faucherre et al., 2011 Fig. 6 with image from Faucherre et al., 2011
kca3Tg; s1006tEt Fig. 6 with image from Faucherre et al., 2011
kca3Tg; ubs3Tg Fig. 7 from Alghisi et al., 2013
kca3Tg; ubs4Tg Fig. S7 from Kobayashi et al., 2014
kca3Tg; vu12Tg Fig. 5 with image from Shin et al., 2007
kca3Tg; vu22Tg Fig. 7 with image from Ozbudak et al., 2008
kca3Tg; y273Tg Fig. 5 with image from Swift et al., 2014 Fig. 5 with image from Swift et al., 2014
mib1ta52b/ta52b; kca3Tg; kca4Tg mib1
mu101Tg ; kca3Tg
pd1Tg ; kca3Tg ; kca4Tg(AB) Fig. 6 from Lee et al., 2014
sox7hu5626/hu5626; hu10049Tg; kca3Tg sox7
ubs3Tg ; rk8Tg ; kca3Tg Fig. 3 from Rochon et al., 2015 Fig. 3 from Rochon et al., 2015
umk4Tg ; kca3Tg Fig. 6 from Taylor et al., 2015 Fig. 6 from Taylor et al., 2015
SEQUENCE INFORMATIONNo data available
OTHER Tg(5xUAS-E1b:6xMYC-notch1a) TRANSGENIC CONSTRUCT PAGESNo links to external sites
CITATIONS (106)