ZFIN ID: ZDB-GENE-020419-32
Gene Name: histone deacetylase 1
Gene Symbol: hdac1
Previous Names: hdac-1 (1), chunp6919, col, colgate, mp:zf637-2-001987, wu:fb19h11 (1), wu:fi06f03 (1), zgc:101582, zgc:65818 (1)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 16 figures from 8 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6904025]
  7 figures (9 images) from Thisse et al., 2008 [MGC:101582]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  anatomical structure, brain, eye, hindbrain (all 12) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
b382 Point Mutation ENU
hi1618Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi2628Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013452Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • rw399 Point Mutation
    s436 Point Mutation
    t22925 Point Mutation
  • European Zebrafish Resource Center (EZRC) (order this)
  • t23715 Point Mutation
  • European Zebrafish Resource Center (EZRC) (order this)
  • t24411 Point Mutation
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-hdac1, MO2-hdac1 (1), MO3-hdac1 (1), MO4-hdac1 (1)
    PHENOTYPE
    Data: 32 figures from 13 publications
    Observed in: atrium, brain, cartilage element, caudal fin (all 63) expand
    DISEASE ASSOCIATED WITH hdac1 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process Wnt signaling pathway (more)
    Cellular Component nucleus (more)
    Molecular Function NAD-dependent histone deacetylase activity (H3-K14 specific) (more)
    GO Terms (all 28)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000286 (1)
  • InterPro:IPR003084 (1)
  • InterPro:IPR023801 (1)
  • Pfam:PF00850 (1)
  • EC:3.5.1.98 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hdac1-001 (1) 2242
    ncRNA hdac1-002 (1) 2165
    hdac1-003 (1) 1972
    hdac1-004 (1) 1249
    hdac1-005 (1) 849
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hdac1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    hdac1Contained in: [BAC] CH73-130A3 (1) (order this)
    hdac1Encodes: [EST] fb19h11 (1), fi06f03 (1), IMAGE:6904025 (1) (order this), zf637-2-001987
    [STS] chunp6919
    [cDNA] MGC:65818 (order this), MGC:101582 (1) (order this), MGC:193070 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173236 (1) 2213bp
    Genomic GenBank:CU633192 (1) 93120bp
    Select Tool
    Polypeptide UniProtKB:F1R653 (1) 480aa
    Sequence Clusters UniGene:31752 (1)
    Sequence Information (all 30)
    OTHER hdac1 GENE PAGES 
  • Gene:192302 (1)
  • VEGA:OTTDARG00000034709 (1)
  • Ensembl(GRCz10):ENSDARG00000015427 (1)
  • ORTHOLOGY for hdac1 (Chr: 19) 
    Species Symbol Chromosome Accession # Evidence
    Human HDAC1 1
  • Gene:3065
  • OMIM:601241
  • HGNC:4852
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (1)
    Nucleotide sequence comparison (1)
    Mouse Hdac1 4
  • MGI:108086
  • Gene:433759
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (72)