ZFIN ID: ZDB-FISH-150901-2109
Fish name: kca3Tg; kca4Tg
Genotype: kca3Tg; kca4Tg
Targeting Reagent: none

HUMAN DISEASE MODELED by kca3Tg; kca4Tg
No data available
GENE EXPRESSION
Gene expression in kca3Tg; kca4Tg
Expressed Gene Structure Conditions Figures
aldh1a2 blastema, regenerating fin heat shock, physical alteration: anatomical structure Fig. 5 with image from Münch et al., 2013
and1 blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
ascl1a Muller cell control Fig. 5 with image from Wan et al., 2012
ascl1b (not) pancreas primordium heat shock Fig. 5 with image from Ghaye et al., 2015
barx1 pharyngeal arch, pharyngeal arch 1, pharyngeal arch 2 heat shock Fig. 3 with image from Barske et al., 2016
cbfb dorsal aorta, posterior cardinal vein heat shock Fig. 7 from Bresciani et al., 2014
cga hypophysis heat shock Fig. 5 with image from Dutta et al., 2008
col1a2 blastema physical alteration: anatomical structure Fig. 6 with image from Grotek et al., 2013
col10a1a blastema physical alteration: anatomical structure Fig. 6 with image from Grotek et al., 2013
dlx2a pharyngeal arch neural crest cell heat shock Fig. 8 with image from Barske et al., 2016
etv4 blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
gh1 hypophysis heat shock Fig. 5 with image from Dutta et al., 2008
hbegfa Muller cell control Fig. 5 with image from Wan et al., 2012
her4.1 hindbrain control Fig. 6 with image from Coolen et al., 2012
hindbrain, neural plate heat shock Fig. 6 with image from Coolen et al., 2012
Fig. 1 from Yeo et al., 2007
her6 blastema heat shock, physical alteration: anatomical structure Fig. 4 with image from Münch et al., 2013
her15.2 blastema heat shock, physical alteration: anatomical structure Fig. 4 with image from Münch et al., 2013
ilf2 blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
inhbaa blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
lef1 blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
lhx3 adenohypophyseal placode heat shock Fig. 3 with image from Dutta et al., 2008
msx1a blastema, regenerating fin heat shock, physical alteration: anatomical structure Fig. 5 with image from Münch et al., 2013
msx1b blastema, regenerating fin heat shock, physical alteration: anatomical structure Fig. 5 with image from Münch et al., 2013
msx2b blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
myb dorsal aorta, posterior cardinal vein, ventral wall of dorsal aorta hematopoietic stem cell heat shock Fig. 3 with image from Zhang et al., 2015
Fig. 7 from Bresciani et al., 2014
Fig. 4 from Burns et al., 2009
mycb ventral wall of dorsal aorta hematopoietic multipotent progenitor cell heat shock Fig. 2 with image from Lin et al., 2015
neurog1 hindbrain control Fig. 6 with image from Coolen et al., 2012
hindbrain heat shock Fig. 6 with image from Coolen et al., 2012
nkx6.1 pancreas primordium heat shock Fig. 5 with image from Ghaye et al., 2015
odf3b pronephros multi-ciliated epithelial cell heat shock Fig. 7 with image from Li et al., 2014
pcna telencephalon ventricular zone heat shock Fig. 6 from Chapouton et al., 2010
pomca adenohypophysis, neurohypophysis, pars intermedia heat shock Fig. 5 with image from Dutta et al., 2008
prl (not) adenohypophyseal placode, (not) hypophysis heat shock Fig. 3 with imageFig. 5 with image from Dutta et al., 2008
prrx1a pharyngeal arch heat shock Fig. 8 with image from Barske et al., 2016
prrx1b pharyngeal arch heat shock Fig. 8 with image from Barske et al., 2016
runx1 hematopoietic multipotent progenitor cell standard conditions Fig. 3 from Kim et al., 2014
dorsal aorta, hematopoietic multipotent progenitor cell, posterior cardinal vein (all 4) expand heat shock Fig. 7 from Bresciani et al., 2014
Fig. 3 from Kim et al., 2014
Fig. S7 from Kobayashi et al., 2014
Fig. 4 from Burns et al., 2009
runx2b blastema physical alteration: anatomical structure Fig. 6 with image from Grotek et al., 2013
s100b telencephalon ventricular zone heat shock Fig. 6 from Chapouton et al., 2010
shha blastema physical alteration: anatomical structure Fig. 6 with image from Grotek et al., 2013
smyhc1 somite heat shock Fig. 7 with image from Li et al., 2014
stc1 corpuscles of Stannius heat shock Fig. 9 with image from Drummond et al., 2017
tcf7 regenerating fin heat shock, physical alteration: anatomical structure Fig. 6 with image from Münch et al., 2013
tshba (not) hypophysis heat shock Fig. 5 with image from Dutta et al., 2008
ttk blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
wnt5b blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
wnt10a blastema heat shock, physical alteration: anatomical structure Fig. 5 with image from Grotek et al., 2013
PHENOTYPE 
Phenotype in kca3Tg; kca4Tg
Phenotype Conditions Figures
blastema distended, abnormal heat shock, physical alteration: anatomical structure Fig. 6 with image from Münch et al., 2013
blastema increased width, abnormal heat shock, physical alteration: anatomical structure Fig. 4 with image from Münch et al., 2013
blastema swollen, abnormal heat shock, physical alteration: anatomical structure Fig. 4 with image from Münch et al., 2013
blastema cell disorganized, abnormal heat shock, physical alteration: anatomical structure Fig. 4 with image from Münch et al., 2013
blastema cell proliferation increased process quality, abnormal heat shock, physical alteration: anatomical structure Fig. 5 with image from Münch et al., 2013
blood vessel endothelial cell migration disrupted, abnormal heat shock Fig. 3 with image from Leslie et al., 2007
corpuscles of Stannius stc1 expression decreased distribution, abnormal heat shock Fig. 9 with image from Drummond et al., 2017
corpuscles of Stannius cell decreased amount, abnormal heat shock Fig. 9 with image from Drummond et al., 2017
fin regeneration decreased process quality, abnormal heat shock, physical alteration: anatomical structure Fig. 4 with image from Münch et al., 2013
hematopoietic stem cell differentiation disrupted, abnormal heat shock Fig. 4 from Burns et al., 2009
intersegmental vessel decreased length, abnormal heat shock Fig. 3 with image from Leslie et al., 2007
Muller cell proliferative, normal heat shock Fig. 2 from Conner et al., 2014
Muller cell proliferative, normal chemical treatment: purpurogallin, heat shock Fig. 2 from Conner et al., 2014
neural plate morphology, abnormal heat shock Fig. 1 from Yeo et al., 2007
neural plate development process quality, abnormal heat shock Fig. 1 from Yeo et al., 2007
neurogenesis decreased rate, abnormal heat shock Fig. 6 from Chapouton et al., 2010
Notch signaling pathway increased process quality, abnormal heat shock Fig. 6 with image from Coolen et al., 2012
pancreas primordium ascl1b expression absent, abnormal heat shock Fig. 5 with image from Ghaye et al., 2015
pancreas primordium nkx6.1 expression increased amount, abnormal heat shock Fig. 5 with image from Ghaye et al., 2015
pancreatic bud ab2-nkx6 labeling increased distribution, abnormal heat shock Fig. 5 with image from Ghaye et al., 2015
pharyngeal arch barx1 expression decreased amount, abnormal heat shock Fig. 3 with image from Barske et al., 2016
pharyngeal arch prrx1b expression increased amount, abnormal heat shock Fig. 8 with image from Barske et al., 2016
pharyngeal arch prrx1a expression increased amount, abnormal heat shock Fig. 8 with image from Barske et al., 2016
pharyngeal arch 1 barx1 expression decreased amount, abnormal heat shock Fig. 3 with image from Barske et al., 2016
pharyngeal arch 2 barx1 expression decreased amount, abnormal heat shock Fig. 3 with image from Barske et al., 2016
pronephros multi-ciliated epithelial cell decreased amount, abnormal heat shock Fig. 7 with image from Li et al., 2014
regenerating fin caudal fin lepidotrichium malformed, abnormal heat shock, physical alteration: anatomical structure Fig. 6 with image from Münch et al., 2013
regenerating fin ossification decreased process quality, abnormal heat shock, physical alteration: anatomical structure Fig. 6 with image from Münch et al., 2013
secondary motor neuron amount, normal standard conditions Fig. 6 with image from Song et al., 2010
secondary motor neuron spatial pattern, normal standard conditions Fig. 6 with image from Song et al., 2010
secondary motor neuron axon morphology, normal standard conditions Fig. 6 with image from Song et al., 2010
ventral wall of dorsal aorta myb expression decreased amount, abnormal heat shock Fig. 3 with image from Zhang et al., 2015
ventral wall of dorsal aorta myb expression increased amount, abnormal heat shock Fig. 3 with image from Zhang et al., 2015
ventral wall of dorsal aorta hematopoietic multipotent progenitor cell increased amount, abnormal heat shock Fig. 2 with image from Lin et al., 2015
ventral wall of dorsal aorta hematopoietic multipotent progenitor cell mycb expression increased distribution, abnormal heat shock Fig. 2 with image from Lin et al., 2015
ventral wall of dorsal aorta hematopoietic stem cell increased amount, abnormal heat shock Fig. 4 from Burns et al., 2009

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