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General Information
ZIRC
ZFIN ID: ZDB-FIG-190221-6
Gerri et al., 2018 - Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. Blood   131(9):963-973 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage: Prim-25
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Prim-25

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
myb WT control Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-epas1a + MO3-epas1b heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-hif1aa + MO1-hif1ab heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg control Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg + MO1-epas1a + MO3-epas1b heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg + MO1-hif1aa + MO1-hif1ab heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; ubs4Tg standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; ubs4Tg + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; ubs4Tg + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
runx1 WT control Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-epas1a + MO3-epas1b heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
WT + MO1-hif1aa + MO1-hif1ab heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg control Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg + MO1-epas1a + MO3-epas1b heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; kca4Tg + MO1-hif1aa + MO1-hif1ab heat shock Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; ubs4Tg standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; ubs4Tg + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
kca3Tg; ubs4Tg + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic system ISH
Prim-25 ventral wall of dorsal aorta ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic system myb expression decreased amount, abnormal
Prim-25 hematopoietic system runx1 expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression decreased amount, abnormal
WT + MO1-epas1a + MO3-epas1b heat shock Prim-25 hematopoietic system myb expression decreased amount, abnormal
Prim-25 hematopoietic system runx1 expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression decreased amount, abnormal
WT + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic system runx1 expression decreased amount, abnormal
Prim-25 hematopoietic system myb expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression decreased amount, abnormal
WT + MO1-hif1aa + MO1-hif1ab heat shock Prim-25 hematopoietic system myb expression decreased amount, abnormal
Prim-25 hematopoietic system runx1 expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression decreased amount, abnormal
kca3Tg; kca4Tg heat shock Prim-25 hematopoietic system myb expression increased amount, abnormal
Prim-25 hematopoietic system runx1 expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression increased amount, abnormal
kca3Tg; kca4Tg + MO1-epas1a + MO3-epas1b heat shock Prim-25 hematopoietic system runx1 expression increased amount, abnormal
Prim-25 hematopoietic system myb expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression increased amount, abnormal
kca3Tg; kca4Tg + MO1-hif1aa + MO1-hif1ab heat shock Prim-25 hematopoietic system runx1 expression increased amount, abnormal
Prim-25 hematopoietic system myb expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression increased amount, abnormal
kca3Tg; ubs4Tg standard conditions Prim-25 hematopoietic system runx1 expression increased amount, abnormal
Prim-25 hematopoietic system myb expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression increased amount, abnormal
kca3Tg; ubs4Tg + MO1-epas1a + MO3-epas1b standard conditions Prim-25 hematopoietic system myb expression increased amount, abnormal
Prim-25 hematopoietic system runx1 expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression increased amount, abnormal
kca3Tg; ubs4Tg + MO1-hif1aa + MO1-hif1ab standard conditions Prim-25 hematopoietic system myb expression increased amount, abnormal
Prim-25 hematopoietic system runx1 expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta myb expression increased amount, abnormal
Prim-25 ventral wall of dorsal aorta runx1 expression increased amount, abnormal
Full text @ Blood