ZFIN ID: ZDB-GENE-030131-2416
Gene Name: F11 receptor, tandem duplicate 1
Gene Symbol: f11r.1    Nomenclature History

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Previous Names: f11r, JAM (1), jama (1), wu:fc07c05, zgc:103642

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Exhibits protein heterodimerization activity. Involved in hematopoietic or lymphoid organ development; posterior lateral line development; and regulation of hematopoietic stem cell differentiation. Predicted to localize to bicellular tight junction. Is expressed in several structures, including EVL; digestive system; integument; pronephros; and sensory system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).
Genome Resources: Alliance (1),  Gene:323696 (1),  Ensembl(GRCz11):ENSDARG00000017320 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-f11r.1 N/A 2
MO2-f11r.1 N/A 1
DISEASE ASSOCIATED WITH f11r.1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH f11r.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hematopoietic or lymphoid organ development (more)
Cellular Component integral component of membrane (more)
Molecular Function protein heterodimerization activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA f11r.1-201 (1)    Ensembl 1749
ncRNA f11r.1-002 (1)    Ensembl 849
f11r.1-003 (1)    Ensembl 764
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM f11r.1
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(-2.2f11r:Cre-ERT2,-2.2f11r:EGFP) f11r.1 CreEGFPERT2 Danio rerio 1 2
Tg(-2.2f11r:EGFP) f11r.1 EGFP Danio rerio 1 3
Tg(-5.1f11r:Cre-ERT2,-5.1f11r:EGFP) f11r.1 CreEGFPERT2 Danio rerio 1 2
MARKER RELATIONSHIPS
f11r.1 Contained in: [BAC] CH73-99I6 (1)
f11r.1 Encodes: [EST] fc07c05, IMAGE:7158623 (1)
[cDNA] cssl:d121 (1), cssl:d216 (1), MGC:103642 (1), MGC:191226 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001004667 (1) 1396 nt
Genomic GenBank:CT027580 (1) 33220 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IK10 (1) 303 aa
Sequence Information (all 26)
ORTHOLOGY for f11r.1 ( Chr: 5 )
CITATIONS (30)