ZFIN

ZFIN ID: ZDB-GENE-030516-1

ZFIN ID: ZDB-GENE-030516-1

CITATIONS (132 total)

Gene Name:	gonadotropin-releasing hormone 2
Gene Symbol:	gnrh2

Guo, J., Huang, W., Zhao, X., Ji, N., Chen, K., Shi, Y., Feng, J., Zou, J., Wang, J. (2023) The expanded ISG12 family in zebrafish: ISG12.1 suppresses virus replication via targeting viral phosphoprotein. Developmental and comparative immunology. 142:104672

Ahi, E.P., Brunel, M., Tsakoumis, E., Chen, J., Schmitz, M. (2022) Appetite regulating genes in zebrafish gut; a gene expression study. PLoS One. 17:e0255201

Gonçalves, C., Kareklas, K., Teles, M.C., Varela, S.A.M., Costa, J., Leite, R.B., Paixão, T., Oliveira, R.F. (2022) Phenotypic architecture of sociality and its associated genetic polymorphisms in zebrafish. Genes, brain, and behavior. 21(5):e12809

Rodrigues, M.S., Tovo-Neto, A., Rosa, I.F., Doretto, L.B., Fallah, H.P., Habibi, H.R., Nóbrega, R.H. (2022) Thyroid Hormones Deficiency Impairs Male Germ Cell Development: A Cross Talk Between Hypothalamic-Pituitary-Thyroid, and-Gonadal Axes in Zebrafish. Frontiers in cell and developmental biology. 10:865948

Tsakoumis, E., Ahi, E.P., Schmitz, M. (2022) Impaired leptin signaling causes subfertility in female zebrafish. Molecular and Cellular Endocrinology. 546:111595

Li, Y., Zhao, T., Liu, Y., Lin, H., Li, S., Zhang, Y. (2021) Knockout of tac3 Genes in Zebrafish Shows No Impairment of Reproduction. General and comparative endocrinology. 311:113839

Marvel, M., Levavi-Sivan, B., Wong, T.T., Zmora, N., Zohar, Y. (2021) Gnrh2 maintains reproduction in fasting zebrafish through dynamic neuronal projection changes and regulation of gonadotropin synthesis, oogenesis, and reproductive behaviors. Scientific Reports. 11:6657

Song, Y., Peng, W., Luo, J., Zhu, Z., Hu, W. (2021) Organization of the gonadotropin-inhibitory hormone (Lpxrfa) system in the brain of zebrafish (Danio rerio). General and comparative endocrinology. 304:113722

Bao, M., Zheng, S., Liu, C., Huang, W., Xiao, J., Wu, K. (2020) Perfluorooctane sulfonate exposure alters sexual behaviors and transcriptions of genes in hypothalamic-pituitary-gonadal-liver axis of male zebrafish (Danio rerio). Environmental pollution (Barking, Essex : 1987). 267:115585

Bhuiyan, M.N.H., Kang, H., Choi, J., Lim, S., Kho, Y., Choi, K. (2020) Effects of 3,4-dichloroaniline (3,4-DCA) and 4,4'-methylenedianiline (4,4'-MDA) on sex hormone regulation and reproduction of adult zebrafish (Danio rerio). Chemosphere. 269:128768

Fallah, H.P., Rodrigues, M.S., Corchuelo, S., Nóbrega, R.H., Habibi, H.R. (2020) Role of GnRH isoforms in paracrine/autocrine control of zebrafish (Danio rerio) spermatogenesis. Endocrinology. 161(2):

Jia, M., Teng, M., Tian, S., Yan, J., Meng, Z., Yan, S., Li, R., Zhou, Z., Zhu, W. (2020) Developmental toxicity and neurotoxicity of penconazole enantiomers exposure on zebrafish (Danio rerio). Environmental pollution (Barking, Essex : 1987). 267:115450

Joshi, I., Mohideen, H.S., Nazeer, R.A. (2020) A Meretrix meretrix visceral mass derived peptide inhibits lipopolysaccharide-stimulated responses in RAW264.7 cells and adult zebrafish model. International Immunopharmacology. 90:107140

Liang, Y.Q., Jing, Z., Pan, C.G., Lin, Z., Zhen, Z., Hou, L., Dong, Z. (2020) The progestin norethindrone alters growth, reproductive histology and gene expression in zebrafish (Danio rerio). Chemosphere. 242:125285

Lu, J., Wu, Q., Yang, Q., Li, G., Wang, R., Liu, Y., Duan, C., Duan, S., He, X., Huang, Z., Peng, X., Yan, W., Jiang, J. (2020) Molecular mechanism of reproductive toxicity induced by beta-cypermethrin in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 239:108894

Luo, Y., Chen, H., Li, D., Zhan, M., Hou, L., Dong, W., Luo, Y., Xie, L. (2020) The effects of norethindrone on the ontogeny of gene expression along the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes in zebrafish (Danio rerio). The Science of the total environment. 747:141554

Mo, A., Wang, X., Yuan, Y., Liu, C., Wang, J. (2020) Effects of waterborne exposure to environmentally relevant concentrations of selenite on reproductive function of female zebrafish: A life cycle assessment. Environmental pollution (Barking, Essex : 1987). 270:116237

Rajeswari, J.J., Unniappan, S. (2020) Phoenixin-20 Stimulates mRNAs Encoding Hypothalamo-Pituitary-Gonadal Hormones, is Pro-Vitellogenic, and Promotes Oocyte Maturation in Zebrafish. Scientific Reports. 10:6264

Sun, D., Chen, Q., Zhu, B., Zhao, H., Duan, S. (2020) Multigenerational reproduction and developmental toxicity, and HPG axis gene expression study on environmentally-relevant concentrations of nonylphenol in zebrafish. The Science of the total environment. 764:144259

Teng, M., Wang, C., Song, M., Chen, X., Zhang, J., Wang, C. (2020) Chronic exposure of zebrafish (Danio rerio) to flutolanil leads to endocrine disruption and reproductive disorders. Environmental research. 184:109310

Ahi, E.P., Brunel, M., Tsakoumis, E., Schmitz, M. (2019) Transcriptional study of appetite regulating genes in the brain of zebrafish (Danio rerio) with impaired leptin signalling. Scientific Reports. 9:20166

Cao, J., Wang, G., Wang, T., Chen, J., Wenjing, G., Wu, P., He, X., Xie, L. (2019) Copper caused reproductive endocrine disruption in zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 211:124-136

Houbrechts, A.M., Van Houcke, J., Darras, V.M. (2019) Disruption of deiodinase type 2 in zebrafish disturbs male and female reproduction. The Journal of endocrinology.

Jiao, F., Qiao, K., Jiang, Y., Li, S., Zhao, J., Gui, W. (2019) Integrated thyroid endocrine disrupting effect on zebrafish (Danio rario) larvae via simultaneously repressing type II iodothyronine deiodinase and activating thyroid receptor-mediated signaling following waterborne exposure to trace azocyclotin. Environmental pollution (Barking, Essex : 1987). 255:113328

Kawan, A., Zhang, T., Liu, W., Mukhtar, H., Zhan, C., Zhang, X. (2019) Recovery of reproductive function of female zebrafish from the toxic effects of microcystin-LR exposure. Aquatic toxicology (Amsterdam, Netherlands). 214:105240

Liang, Y.Q., Huang, G.Y., Zhen, Z., Tian, F., Hou, L., Lin, Z., Ying, G.G. (2019) The effects of binary mixtures of estradiol and progesterone on transcriptional expression profiles of genes involved in hypothalamic-pituitary-gonadal axis and circadian rhythm signaling in embryonic zebrafish (Danio rerio). Ecotoxicology and environmental safety. 174:540-548

London, S., Volkoff, H. (2019) Effects of fasting on the central expression of appetite-regulating and reproductive hormones in wild-type and Casper zebrafish (Danio rerio). General and comparative endocrinology. 282:113207

Marvel, M.M., Spicer, O.S., Wong, T.T., Zmora, N., Zohar, Y. (2019) Knockout of Gnrh2 in zebrafish (Danio rerio) reveals its roles in regulating feeding behavior and oocyte quality. General and comparative endocrinology. 280:15-23

Paredes, J.F., Cowan, M., López-Olmeda, J.F., Muñoz-Cueto, J.A., Sánchez-Vázquez, F.J. (2019) Daily rhythms of expression in reproductive genes along the brain-pituitary-gonad axis and liver of zebrafish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 231:158-169

Peng, X., Sun, X., Yu, M., Fu, W., Chen, H., Chen, J. (2019) Chronic exposure to environmental concentrations of phenanthrene impairs zebrafish reproduction. Ecotoxicology and environmental safety. 182:109376

Shi, G., Cui, Q., Zhang, H., Cui, R., Guo, Y., Dai, J. (2019) Accumulation, Biotransformation, and Endocrine Disruption Effects of Fluorotelomer Surfactant Mixtures on Zebrafish. Chemical Research in Toxicology. 32(7):1432-1440

Shi, W.J., Ma, D.D., Jiang, Y.X., Xie, L., Zhang, J.N., Huang, G.Y., Chen, H.X., Hou, L.P., Liu, Y.S., Ying, G.G. (2019) Medroxyprogesterone acetate affects sex differentiation and spermatogenesis in zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 212:70-76

Teng, M., Chen, X., Wang, C., Song, M., Zhang, J., Bi, S., Wang, C. (2019) Life cycle exposure to propiconazole reduces fecundity by disrupting the steroidogenic pathway and altering DNA methylation in zebrafish (Danio rerio). Environment International. 135:105384

Xie, X., Jin, Y., Ma, Z., Tang, S., Peng, H., Giesy, J.P., Liu, H. (2019) Underlying mechanisms of reproductive toxicity caused by multigenerational exposure of 2, bromo-4, 6-dinitroaniline (BDNA) to Zebrafish (Danio rerio) at environmental relevant levels. Aquatic toxicology (Amsterdam, Netherlands). 216:105285

Zhang, H., Chen, Z.F., Qi, Z., Yan, S.C., Wei, W.W., Liu, G., Cai, Z. (2019) ANALYSIS OF TRANSCRIPTIONAL RESPONSE IN ZEBRAFISH ELEUTHEROEMBRYOS EXPOSED TO CLIMBAZOLE: SIGNALING PATHWAYS AND POTENTIAL BIOMARKERS. Environmental toxicology and chemistry. 38(4):794-805

Branco, G.S., Melo, A.G., Ricci, J.M.B., Digmayer, M., de Jesus, L.W.O., Habibi, H.R., Nóbrega, R.H. (2018) Effects of GnRH and the dual regulatory actions of GnIH in the pituitary explants and brain slices of Astyanax altiparanae males. General and comparative endocrinology. 273:209-217

Hou, J., Su, Y., Lin, W., Guo, H., Li, L., Anderson, D.M., Li, D., Tang, R., Chi, W., Zhang, X. (2018) Estrogenic potency of MC-LR is induced via stimulating steroidogenesis: In vitro and in vivo evidence. Environmental pollution (Barking, Essex : 1987). 240:615-622

Hou, L.P., Shu, H., Lin, L.L., Xu, S.Y., Wu, Y.X., Rong, X.J., Hu, J.J., Song, L.Y., Liang, Y.Q., Chen, H.X., Ying, G.G., Tian, C.E. (2018) Modulation of transcription of genes related to the hypothalamic-pituitary-gonadal and the hypothalamic-pituitary-adrenal axes in zebrafish (Danio rerio) embryos/larvae by androstenedione. Ecotoxicology and environmental safety. 156:403-408

Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations. Chemosphere. 218:449-457

Jiang, J., Lv, L., Wu, S., An, X., Wang, F., Liu, X., Zhao, X. (2018) Developmental toxicity of kresoxim-methyl during zebrafish (Danio rerio) larval development. Chemosphere. 219:517-525

Lee, J., Park, N.Y., Kho, Y., Ji, K. (2018) Effects of 4-Hydroxyphenyl 4-Isoprooxyphenylsulfone (BPSIP) Exposure on Reproduction and Endocrine System of Zebrafish. Environmental science & technology. 52(3):1506-1513

Liang, Y.Q., Huang, G.Y., Lin, Z., Li, J., Yang, J.W., Zhong, L.Y., Ying, G.G. (2018) Reproductive effects of synthetic progestin norgestrel in zebrafish (Danio rerio). Chemosphere. 190:17-24

Lin, W., Guo, H., Li, Y., Wang, L., Zhang, D., Hou, J., Wu, X., Li, L., Li, D., Zhang, X. (2018) Single and combined exposure of microcystin-LR and nitrite results in reproductive endocrine disruption via hypothalamic-pituitary-gonadal-liver axis. Chemosphere. 211:1137-1146

Loganathan, K., Moriya, S., Parhar, I.S. (2018) High Melatonin Conditions by Constant Darkness and High Temperature Differently Affect Melatonin Receptor mt1 and TREK Channel trek2a in the Brain of Zebrafish. Zebrafish. 15(5):473-483

Marvel, M., Spicer, O.S., Wong, T.T., Zmora, N., Zohar, Y. (2018) Knockout of the Gnrh genes in zebrafish: effects on reproduction and potential compensation by reproductive and feeding-related neuropeptides. Biology of reproduction. 99(3):565-577

Shi, G., Guo, H., Sheng, N., Cui, Q., Pan, Y., Wang, J., Guo, Y., Dai, J. (2018) Two-generational reproductive toxicity assessment of 6:2 chlorinated polyfluorinated ether sulfonate (F-53B, a novel alternative to perfluorooctane sulfonate) in zebrafish. Environmental pollution (Barking, Essex : 1987). 243:1517-1527

Shi, W.J., Hu, L.X., Huang, G.Y., Liu, Y.S., Zhang, J.N., Xie, L., Ying, G.G. (2018) Dydrogesterone affects the transcription of genes in GnRH and steroidogenesis pathways and increases the frequency of atretic follicles in zebrafish (Danio rerio). Chemosphere. 216:725-732

Sun, W., Jia, Y., Ding, X., Dai, L., Liu, C., Wang, J., Zhao, G., Zhou, H., Yu, L. (2018) Combined effects of pentachlorophenol and its byproduct hexachlorobenzene on endocrine and reproduction in zebrafish. Chemosphere. 220:216-226

Wang, Y., Dai, D., Yu, Y., Yang, G., Shen, W., Wang, Q., Weng, H., Zhao, X. (2018) Evaluation of joint effects of cyprodinil and kresoxim-methyl on zebrafish, Danio rerio. Journal of hazardous materials. 352:80-91

Zhang, Y., Li, M., Li, S., Wang, Q., Zhu, G., Su, G., Letcher, R.J., Liu, C. (2018) Exposure to tris(1,3-dichloro-2-propyl) phosphate for Two generations decreases fecundity of zebrafish at environmentally relevant concentrations. Aquatic toxicology (Amsterdam, Netherlands). 200:178-187

Chen, S., Reichert, S., Singh, C., Oikonomou, G., Rihel, J., Prober, D.A. (2017) Light-Dependent Regulation of Sleep and Wake States by Prokineticin 2 in Zebrafish. Neuron. 95(1):153-168.e6

Chen, W., Lau, S.W., Fan, Y., Wu, R.S.S., Ge, W. (2017) Juvenile exposure to bisphenol A promotes ovarian differentiation but suppresses its growth - Potential involvement of pituitary follicle-stimulating hormone. Aquatic toxicology (Amsterdam, Netherlands). 193:111-121

Corchuelo, S., Martinez, E.R., Butzge, A.J., Doretto, L.B., Valentin, T.N., Nakaghi, L.S., Somoza, G.M., Nóbrega, R.H. (2017) Characterization of Gnrh/Gnih elements in the olfacto-retinal system and ovary during zebrafish ovarian maturation. Molecular and Cellular Endocrinology. 450:1-13

Liang, Y.Q., Huang, G.Y., Zhao, J.L., Shi, W.J., Hu, L.X., Tian, F., Liu, S.S., Jiang, Y.X., Ying, G.G. (2017) Transcriptional alterations induced by binary mixtures of ethinylestradiol and norgestrel during the early development of zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 195:60-67

Liu, G., Ke, M., Fan, X., Zhang, M., Zhu, Y., Lu, T., Sun, L., Qian, H. (2017) Reproductive and endocrine-disrupting toxicity of Microcystis aeruginosa in female zebrafish. Chemosphere. 192:289-296

Liu, Y., Tang, H., Xie, R., Li, S., Liu, X., Lin, H., Zhang, Y., Cheng, C.H. (2017) Genetic Evidence for Multifactorial Control of the Reproductive Axis in Zebrafish. Endocrinology. 158:604-611

Shi, W.J., Ying, G.G., Huang, G.Y., Liang, Y.Q., Hu, L.X., Zhao, J.L., Zhang, J.N. (2017) Transcriptional and Biochemical Alterations in Zebrafish Eleuthero-Embryos (Danio rerio) After Exposure to Synthetic Progestogen Dydrogesterone. Bulletin of environmental contamination and toxicology. 99(1):39-45

Spicer, O.S., Zmora, N., Wong, T.T., Golan, M., Levavi-Sivan, B., Gothilf, Y., Zohar, Y. (2017) The GNIH (Lpxrfa) system's regulation of reproduction in the brain-pituitary axis of the zebrafish (Danio rerio). Biology of reproduction. 96(5):1031-1042

Teng, M., Qi, S., Zhu, W., Wang, Y., Wang, D., Dong, K., Wang, C. (2017) Effects of the bioconcentration and parental transfer of environmentally relevant concentrations of difenoconazole on endocrine disruption in zebrafish (Danio rerio). Environmental pollution (Barking, Essex : 1987). 233:208-217

Xu, Q., Wu, D., Dang, Y., Yu, L., Liu, C., Wang, J. (2017) Reproduction impairment and endocrine disruption in adult zebrafish (Danio rerio) after waterborne exposure to TBOEP. Aquatic toxicology (Amsterdam, Netherlands). 182:163-171

Yan, Y.L., Desvignes, T., BreMiller, R., Wilson, C., Dillon, D., High, S., Draper, B., Buck, C.L., Postlethwait, J. (2017) The gonadal soma controls ovarian follicle proliferation through Gsdf in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 246(11):925-945

Yang, Q., Yang, X., Liu, J., Ren, W., Chen, Y., Shen, S. (2017) Effects of BPF on steroid hormone homeostasis and gene expression in the hypothalamic-pituitary-gonadal axis of zebrafish. Environmental science and pollution research international. 24(26):21311-21322

Yu, M., Feng, Y., Zhang, X., Wang, J., Tian, H., Wang, W., Ru, S. (2017) Semicarbazide disturbs the reproductive system of male zebrafish (Danio rerio) through the GABAergic system. Reproductive toxicology (Elmsford, N.Y.). 73:149-157

Dang, Y., Wang, J., Giesy, J.P., Liu, C. (2016) Responses of the zebrafish hypothalamic-pituitary-gonadal-liver axis PCR array to prochloraz are dependent on timing of sampling. Aquatic toxicology (Amsterdam, Netherlands). 175:154-159

Hou, J., Li, L., Wu, N., Su, Y., Lin, W., Li, G., Gu, Z. (2016) Reproduction impairment and endocrine disruption in female zebrafish after long-term exposure to MC-LR: A life cycle assessment. Environmental pollution (Barking, Essex : 1987). 208(Pt B):477-85

Kang, H., Moon, H.B., Choi, K. (2016) Toxicological responses following short-term exposure through gavage feeding or water-borne exposure to Dechlorane Plus in zebrafish (Danio rerio). Chemosphere. 146:226-232

Khor, Y.M., Soga, T., Parhar, I.S. (2016) Early-Life Stress Changes Expression of GnRH and Kisspeptin Genes and DNA Methylation of GnRH3 Promoter in The Adult Zebrafish Brain. General and comparative endocrinology. 227:84-93

Kwon, B., Ha, N., Jung, J., Kim, P.G., Kho, Y., Choi, K., Ji, K. (2016) Effects of Barium Chloride Exposure on Hormones and Genes of the Hypothalamic-Pituitary-Gonad Axis, and Reproduction of Zebrafish (Danio rerio). Bulletin of environmental contamination and toxicology. 96(3):341-6

Kwon, B., Shin, H., Moon, H.B., Ji, K., Kim, K.T. (2016) Effects of tris(2-butoxyethyl) phosphate exposure on endocrine systems and reproduction of zebrafish (Danio rerio). Environmental pollution (Barking, Essex : 1987). 214:568-574

Liu, W., Chen, C., Chen, L., Wang, L., Li, J., Chen, Y., Jin, J., Kawan, A., Zhang, X. (2016) Sex-dependent effects of microcystin-LR on hypothalamic-pituitary-gonad axis and gametogenesis of adult zebrafish. Scientific Reports. 6:22819

Liu, X., Jung, D., Jo, A., Ji, K., Moon, H.B., Choi, K. (2016) Long-term exposure to triphenyl phosphate alters hormone balance and HPG, HPI, and HPT gene expression in zebrafish (Danio rerio). Environmental toxicology and chemistry. 35(9):2288-96

Ma, Z., Tang, S., Su, G., Miao, Y., Liu, H., Xie, Y., Giesy, J.P., Saunders, D.M., Hecker, M., Yu, H. (2016) Effects of tris (2-butoxyethyl) phosphate (TBOEP) on endocrine axes during development of early life stages of zebrafish (Danio rerio). Chemosphere. 144:1920-1927

Su, Y., Li, L., Hou, J., Wu, N., Lin, W., Li, G. (2016) Life-cycle exposure to microcystin-LR interferes with the reproductive endocrine system of male zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 175:205-212

Yu, M., Zhang, X., Guo, L., Tian, H., Wang, W., Ru, S. (2016) Anti-estrogenic effect of semicarbazide in female zebrafish (Danio rerio) and its potential mechanisms. Aquatic toxicology (Amsterdam, Netherlands). 170:262-270

Zhang, Q.F., Li, Y.W., Liu, Z.H., Chen, Q.L. (2016) Reproductive toxicity of inorganic mercury exposure in adult zebrafish: Histological damage, oxidative stress, and alterations of sex hormone and gene expression in the hypothalamic-pituitary-gonadal axis. Aquatic toxicology (Amsterdam, Netherlands). 177:417-424

Zhao, Y., Zhang, K., Fent, K. (2016) Corticosteroid Fludrocortisone Acetate Targets Multiple End Points in Zebrafish (Danio rerio) at Low Concentrations. Environmental science & technology. 50(18):10245-54

Huang, Y., Linsen, S.E. (2015) Partial depletion of yolk during zebrafish embryogenesis changes the dynamics of methionine cycle and metabolic genes. BMC Genomics. 16:427

Liang, Y.Q., Huang, G.Y., Ying, G.G., Liu, S.S., Jiang, Y.X., Liu, S., Peng, F.J. (2015) A time-course transcriptional kinetics of the hypothalamic-pituitary-gonadal and hypothalamic-pituitary-adrenal axes in zebrafish eleuthero-embryos after exposure to norgestrel. Environmental toxicology and chemistry. 34(1):112-9

Liang, Y.Q., Huang, G.Y., Ying, G.G., Liu, S.S., Jiang, Y.X., Liu, S., Peng, F.J. (2015) The effects of progesterone on transcriptional expression profiles of genes associated with hypothalamic-pituitary-gonadal and hypothalamic-pituitary-adrenal axes during the early development of zebrafish (Danio rerio). Chemosphere. 128C:199-206

Prasad, P., Ogawa, S., Parhar, I.S. (2015) Serotonin Reuptake Inhibitor Citalopram Inhibits GnRH synthesis and Spermatogenesis in the Male Zebrafish. Biology of reproduction. 93(4):102

Shi, J., Jiao, Z., Zheng, S., Li, M., Zhang, J., Feng, Y., Yin, J., Shao, B. (2015) Long-term effects of Bisphenol AF (BPAF) on hormonal balance and genes of hypothalamus-pituitary-gonad axis and liver of zebrafish (Danio rerio), and the impact on offspring. Chemosphere. 128C:252-257

Wang, F., Huang, G.D., Tian, H., Zhong, Y.B., Shi, H.J., Li, Z., Zhang, X.S., Wang, H., Sun, F. (2015) Point mutations in KAL1 and the mitochondrial gene MT-tRNA(cys) synergize to produce Kallmann syndrome phenotype. Scientific Reports. 5:13050

Zhao, Y., Castiglioni, S., Fent, K. (2015) Environmental progestins progesterone and drospirenone alter the circadian rhythm network in zebrafish (Danio rerio). Environmental science & technology. 49(16):10155-64

Zhao, Y., Xie, L., Yan, Y. (2015) Microcystin-LR impairs zebrafish reproduction by affecting oogenesis and endocrine system. Chemosphere. 120C:115-122

Han, J., Wang, Q., Wang, X., Li, Y., Wen, S., Liu, S., Ying, G., Guo, Y., Zhou, B. (2014) The synthetic progestin megestrol acetate adversely affects zebrafish reproduction. Aquatic toxicology (Amsterdam, Netherlands). 150:66-72

Jo, A., Ji, K., Choi, K. (2014) Endocrine disruption effects of long-term exposure to perfluorodecanoic acid (PFDA) and perfluorotridecanoic acid (PFTrDA) in zebrafish (Danio rerio) and related mechanisms. Chemosphere. 108:360-6

Xia, W., Smith, O., Zmora, N., Xu, S., and Zohar, Y. (2014) Comprehensive analysis of GnRH2 neuronal projections in zebrafish. Scientific Reports. 4:3676

Ji, K., Hong, S., Kho, Y., and Choi, K. (2013) Effects of bisphenol S exposure on endocrine functions and reproduction of zebrafish. Environmental science & technology. 47(15):8793-800

Ji, K., Liu, X., Lee, S., Kang, S., Kho, Y., Giesy, J.P., and Choi, K. (2013) Effects of non-steroidal anti-inflammatory drugs on hormones and genes of the hypothalamic-pituitary-gonad axis, and reproduction of zebrafish. Journal of hazardous materials. 254-255C:242-251

Jung Collard, H.R., Ji, K., Lee, S., Liu, X., Kang, S., Kho, Y., Ahn, B., Ryu, J., Lee, J., and Choi, K. (2013) Toxicity and endocrine disruption in zebrafish (Danio rerio) and two freshwater invertebrates (Daphnia magna and Moina macrocopa) after chronic exposure to mefenamic acid. Ecotoxicology and environmental safety. 94:80-86

Schiller, V., Wichmann, A., Kriehuber, R., Schäfers, C., Fischer, R., and Fenske, M. (2013) Transcriptome alterations in zebrafish embryos after exposure to environmental estrogens and anti-androgens can reveal endocrine disruption. Reproductive toxicology (Elmsford, N.Y.). 42:210-23

Shahjahan, M., Kitahashi, T., Ogawa, S., and Parhar, I.S. (2013) Temperature differentially regulates the two kisspeptin systems in the brain of zebrafish. General and comparative endocrinology. 193C:79-85

Zucchi, S., Castiglioni, S., and Fent, K. (2013) Progesterone Alters Global Transcription Profiles at Environmental Concentrations in Brain and Ovary of Female Zebrafish (Danio rerio). Environmental science & technology. 47(21):12548-56

Biran, J., Palevitch, O., Ben-Dor, S., and Levavi-Sivan, B. (2012) Neurokinin Bs and neurokinin B receptors in zebrafish-potential role in controlling fish reproduction. Proceedings of the National Academy of Sciences of the United States of America. 109(26):10269-10274

Nishiguchi, R., Azuma, M., Yokobori, E., Uchiyama, M., and Matsuda, K. (2012) Gonadotropin-releasing hormone 2 suppresses food intake in the zebrafish, Danio rerio. Frontiers in Experimental Endocrinology. 3:122

Bhattacharya, P., Yan, Y.L., Postlethwait, J., and Rubin, D. (2011) Evolution of the vertebrate pth2 (tip39) gene family and the regulation of PTH type 2 receptor (pth2r) and its endogenous ligand pth2 by hedgehog signaling in zebrafish development. The Journal of endocrinology. 211(2):187-200

Han, X.B., Lei, E.N., Lam, M.H., and Wu, R.S. (2011) A whole life cycle assessment on effects of waterborne PBDEs on gene expression profile along the brain-pituitary-gonad axis and in the liver of zebrafish. Marine pollution bulletin. 63(5-12):160-5

Liu, C., Zhang, X., Deng, J., Hecker, M., Al-Khedhairy, A., Giesy, J.P., and Zhou, B. (2011) Effects of Prochloraz or Propylthiouracil on the Cross-Talk between the HPG, HPA, and HPT Axes in Zebrafish. Environmental science & technology. 45(2):769-775

Onuma, T.A., Ding, Y., Abraham, E., Zohar, Y., Ando, H., and Duan, C. (2011) Regulation of Temporal and Spatial Organization of Newborn GnRH Neurons by IGF Signaling in Zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(33):11814-11824

Ríos, Y., Melmed, S., Lin, S., and Liu, N.A. (2011) Zebrafish usp39 Mutation Leads to rb1 mRNA Splicing Defect and Pituitary Lineage Expansion. PLoS Genetics. 7(1):e1001271

Filby, A.L., Paull, G.C., Hickmore, T.F., and Tyler, C.R. (2010) Unravelling the neurophysiological basis of aggression in a fish model. BMC Genomics. 11:498

Stockhammer, O.W., Rauwerda, H., Wittink, F.R., Breit, T.M., Meijer, A.H., and Spaink, H.P. (2010) Transcriptome analysis of Traf6 function in the innate immune response of zebrafish embryos. Molecular immunology. 48(1-3):179-190

Kitahashi, T., Ogawa, S., and Parhar, I.S. (2009) Cloning and expression of kiss2 in the zebrafish and medaka. Endocrinology. 150(2):821-831

Liu, C., Yu, L., Deng, J., Lam, P.K., Wu, R.S., and Zhou, B. (2009) Waterborne exposure to fluorotelomer alcohol 6:2 FTOH alters plasma sex hormone and gene transcription in the hypothalamic-pituitary-gonadal (HPG) axis of zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 93(2-3):131-137

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Additional Citations (15):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.