Figure 8

García-González et al., 2020 - Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour
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Figure 8

Quantitative real-time PCR analysis of five-day-old wild type <italic>slit3<sup>sa1569+/+</sup></italic>, <italic>slit3<sup>sa1569/+</sup></italic> heterozygous and <italic>slit3<sup>sa1569/sa1569</sup></italic> homozygous mutant larvae.

Quantitative PCR analysis of gene expression was performed for members of (A) dopaminergic signalling pathway, (B) adrenoreceptors, (C) serotonin signalling pathway and (D) nicotinic cholinergic receptors. (Total n=30, 3 samples per experimental group with n=10 embryos per sample). Only htr1aa ([F(2,6)=44], p=0.0003) showed a significant difference across genotypes after correcting for multiple testing. *Two-way ANOVA followed by post-hoc Tukey test (p < 0.05).

Gene expression data for <italic>slit3</italic> mutant and wild type zebrafish.

Expression Data
Anatomical Term:
Stage: Day 5

Expression Detail
Antibody Labeling
Phenotype Data
Observed In:
Stage: Day 5

Phenotype Detail
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