Gene
adra2b
- ID
- ZDB-GENE-021010-2
- Name
- adrenoceptor alpha 2B
- Symbol
- adra2b Nomenclature History
- Previous Names
-
- fb43d01
- wu:fb43d01 (1)
- zgc:194747
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits alpha2-adrenergic receptor activity. Involved in adenylate cyclase-inhibiting adrenergic receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in diabetic neuropathy; hypertension; myocardial infarction; obesity; and type 2 diabetes mellitus. Is expressed in several structures, including digestive system; eye; heart; integument; and pleuroperitoneal region. Orthologous to human ADRA2B (adrenoceptor alpha 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|
|
UniProtKB:Q90WY5
|
510 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adra2b-201
(1)
|
Ensembl | 1,581 nt |
Interactions and Pathways
No data available
Plasmids
No data available