Gene

htr1b

ID

ZDB-GENE-081022-141

Name

5-hydroxytryptamine (serotonin) receptor 1B

Symbol

htr1b Nomenclature History

Previous Names

zgc:194666
zgc:194690

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have G protein-coupled serotonin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to localize to dendrite and integral component of plasma membrane. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and conduct disorder. Is expressed in central nervous system; pharynx; and retina. Orthologous to human HTR1B (5-hydroxytryptamine receptor 1B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UCSC scRNA-seq

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With htr1b Human Ortholog

No data available

Associated With htr1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR002147	5-Hydroxytryptamine 1B receptor
Family	IPR002231	5-hydroxytryptamine receptor family