ZFIN is now using GRCz12tu for Genomic Data
Gene
htr1b
- ID
- ZDB-GENE-081022-141
- Name
- 5-hydroxytryptamine (serotonin) receptor 1B
- Symbol
- htr1b Nomenclature History
- Previous Names
-
- zgc:194666
- zgc:194690
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Acts upstream of or within peripheral nervous system axon regeneration and serotonergic neuron axon guidance. Predicted to be located in membrane and synapse. Predicted to be active in dendrite and plasma membrane. Is expressed in central nervous system; male organism; pharynx; and retina. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; antisocial personality disorder; attention deficit hyperactivity disorder; conduct disorder; and substance abuse (multiple). Orthologous to human HTR1B (5-hydroxytryptamine receptor 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | 5-Hydroxytryptamine 1B receptor | 5-hydroxytryptamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|---|
| UniProtKB:B3DK14 | InterPro | 380 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers