FIGURE

Figure 1

ID

ZDB-FIG-200406-224

Publication

García-González et al., 2020 - Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

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Figure 1

Inhibition of nicotine CPP by varenicline and bupropion.
10 μM nicotine induced place preference in zebrafish is sensitive to inhibition by therapeutics effective in humans. (A) Varenicline (nicotine partial agonist) and (B) Bupropion (norepinephrine and dopamine reuptake inhibitor with nicotine antagonist properties when metabolised). Bars represent mean and error bars represent + SEM. Asterisk (*) represents significance at p<0.05. Figure 1—source data 1.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: nicotine chemical treatment by environment: nicotine chemical treatment by environment: nicotine
Observed In:	conditioned place preference
Stage:	Adult

Phenotype Detail

Acknowledgments

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