Transgenic Construct

Tg(EPV.Tp1-Mmu.Hbb:Venus-Mmu.Odc1)

ID

ZDB-TGCONSTRCT-120419-4

Previous Names

Tg(EPV.TP1-Mmu.Hbb:Venus-Mmu.Odc1)
Tg(TP1bglob:VenusPEST) (1)
TP1:VenusPEST (1)

Type

engineered_plasmid

Regulatory Regions

None

Coding Sequences

Venus (1)

[Em λ][Ex λ]

Fpbase:Venus

Contains Sequences

T2K (1)

Note

This construct is designed to express destabilized Venus protein in regions of strong Notch activity. (Ninov et al. 2012, PMID: 22492351). The PEST region of mouse ornithine decarboxylase (422-461) was fused to Venus. PEST regions appear to be correlated with protein degradation (Li et al. 1998 PMID: 9857028)

Plasmid Map

None

Genomic Features

That Utilize Tg(EPV.Tp1-Mmu.Hbb:Venus-Mmu.Odc1) Construct

Genomic Feature	Affected Genomic Regions
s940Tg

Transgenics

That Utilize Tg(EPV.Tp1-Mmu.Hbb:Venus-Mmu.Odc1) Construct

Fish	Affected Genomic Regions	Phenotype	Gene Expression
ccm2^m201/m201; s940Tg	ccm2	Fig. 4 from Donat et al., 2018	Fig. 4 from Donat et al., 2018
co17Tg; s939Tg; s940Tg			Fig. 6 from So et al., 2017
cu2Tg; s940Tg		Fig. 2 from MacDonald et al., 2015	2 figures from MacDonald et al., 2015
fbxw7^vu56/+; hdac1^b382/+; s939Tg/+; s940Tg/+	fbxw7 hdac1
fbxw7^vu56/+; hdac1^b382/+; s939Tg/s939Tg; s940Tg/s940Tg	fbxw7 hdac1	Fig. 5 from Ko et al., 2018	Fig. 5 from Ko et al., 2018
fbxw7^vu56/+; s939Tg/s939Tg; s940Tg/s940Tg	fbxw7	Fig. 5 from Ko et al., 2018	Fig. 5 from Ko et al., 2018
gt1Tg; jh11Tg; s940Tg
gt1Tg; s939Tg; s940Tg		Fig. S12 from Huang et al., 2014	3 figures from Huang et al., 2014
gt1Tg; s940Tg
hdac1^b382/+; s939Tg/s939Tg; s940Tg/s940Tg	hdac1	Fig. 5 from Ko et al., 2018	2 figures from Ko et al., 2018
ia5Tg; kca3Tg; mu286Tg; s940Tg		Figure 4 from Paolini et al., 2021	Figure 4 from Paolini et al., 2021
ia5Tg; mu201Tg; s898Tg; s940Tg		Figure 2 from Paolini et al., 2021	Figure 2 from Paolini et al., 2021
ia5Tg; s940Tg		Figure 4 from Paolini et al., 2021	4 figures from Paolini et al., 2021
ia5Tg; s940Tg + MO2-fzd9b		Figure 4 from Paolini et al., 2021	Figure 4 from Paolini et al., 2021
ia5Tg; s940Tg + MO3-wnt9a		Figure 3 from Paolini et al., 2021	Figure 3 from Paolini et al., 2021
kdm1a^it627/+; s931Tg/s931Tg; s939Tg/s939Tg; s940Tg/s940Tg	kdm1a	Fig. 6 from Ko et al., 2018	Fig. 6 from Ko et al., 2018
kdm1a^it627/it627; s931Tg/s931Tg; s939Tg/s939Tg; s940Tg/s940Tg	kdm1a	Fig. 6 from Ko et al., 2018	Fig. 6 from Ko et al., 2018
kdm1a^it627/it627; s939Tg/s939Tg; s940Tg/s940Tg	kdm1a	Fig. 6 from Ko et al., 2018	Fig. 6 from Ko et al., 2018
klf2a^sh317/sh317; klf2b^pbb42/pbb42; ia5Tg; s940Tg	klf2a klf2b	Figure 2 from Paolini et al., 2021	Figure 2 from Paolini et al., 2021
md12Tg; s940Tg			Fig. 2 from Donat et al., 2018
md6Tg; s940Tg			Fig. 2 from Donat et al., 2018
nl1Tg; s924Tg; s940Tg			Fig. 3 from Ninov et al., 2013
nl1Tg; s924Tg; s940Tg; s954Tg			Fig. 3 from Ninov et al., 2013
nns17Tg; s940Tg			Fig. 1 from MacDonald et al., 2015
notch1b^{ion35h/ion35h}; s940Tg/s940Tg	notch1b	Fig. 6 from Jin et al., 2022	Fig. 6 from Jin et al., 2022
notch3^fh332/+; s939Tg/s939Tg; s940Tg/s940Tg	notch3	Fig. 5 from Ko et al., 2018	Fig. 5 from Ko et al., 2018
notch3^fh332/fh332; s939Tg/s939Tg; s940Tg/s940Tg	notch3	Fig. 5 from Ko et al., 2018	Fig. 5 from Ko et al., 2018
notch3^{ion36h/ion36h}; s940Tg/s940Tg	notch3	Fig. 6 from Jin et al., 2022	Fig. 6 from Jin et al., 2022
nrg2a^{mn0237Gt/mn0237Gt}; s940Tg	nrg2a	Fig. 6 from Jiménez-Amilburu et al., 2016	Fig. 6 from Jiménez-Amilburu et al., 2016
rbx1^{bns148/bns148}; s896Tg; s940Tg	rbx1	Fig. 4 from Sarvari et al., 2021	Fig. 4 from Sarvari et al., 2021
rbx1^{bns148/bns148}; s940Tg; sd11Tg	rbx1	Fig. 4 from Sarvari et al., 2021	Fig. 4 from Sarvari et al., 2021
s843Tg; s940Tg			Fig. 5 from Kempers et al., 2021
s843Tg; s940Tg + MO1-rab5c			Fig. 5 from Kempers et al., 2021
s896Tg; s940Tg		Fig. 4 from Sarvari et al., 2021	Fig. 4 from Sarvari et al., 2021
s931Tg/s931Tg; s939Tg/s939Tg; s940Tg/s940Tg
s931Tg; s939Tg; s940Tg		2 figures from 2 publications	6 figures from 2 publications
s931Tg; s939Tg; s940Tg; w30Tg		Fig. 2 from Choi et al., 2017	Fig. 2 from Choi et al., 2017
s939Tg/s939Tg; s940Tg/s940Tg		2 figures from Ko et al., 2018	5 figures from Ko et al., 2018
s939Tg; s940Tg		Fig. 4 from So et al., 2017	6 figures from 5 publications
s939Tg; s940Tg + MO1-lnx2a			Fig. 6 from Won et al., 2015
s939Tg; s940Tg + MO1-lnx2a + MO4-numb			Fig. 6 from Won et al., 2015
s939Tg; s940Tg + MO4-numb			Fig. 6 from Won et al., 2015
s939Tg; s940Tg; w35Tg		Fig. 4 from So et al., 2017	Fig. 4 from So et al., 2017
s940Tg		2 figures from 2 publications	7 figures from 5 publications
s940Tg + CRISPR1-irx3b + CRISPR2-irx3b		Fig. 6 from Naylor et al., 2018	Fig. 6 from Naylor et al., 2018
s940Tg + MO1-tnnt2a		Fig. 6 from Jiménez-Amilburu et al., 2016	Fig. 6 from Jiménez-Amilburu et al., 2016
s940Tg/s940Tg			2 figures from 2 publications
s940Tg/s940Tg + MO1-prmt5		Fig. 3 from Quillien et al., 2021	Fig. 3 from Quillien et al., 2021
s940Tg/s940Tg; um13Tg/um13Tg		Fig. 3 from Kapuria et al., 2022
s940Tg; sd11Tg		Fig. 4 from Sarvari et al., 2021	2 figures from 2 publications
s940Tg; sd21Tg			Fig. 5 from Jiménez-Amilburu et al., 2016
s940Tg; vc6Tg			2 figures from Samsa et al., 2015
s940Tg; vc6Tg + MO1-ift88 + MO3-ift88		Fig. 6 from Samsa et al., 2015	Fig. 6 from Samsa et al., 2015
smad5^m169/m169; s931Tg; s939Tg; s940Tg	smad5		Fig. 5 from Choi et al., 2017
sox9b^fh313/fh313; s939Tg; s940Tg	sox9b	Fig. 7 from Delous et al., 2012	Fig. 7 from Delous et al., 2012
tbx2b^c144/c144; s931Tg; s939Tg; s940Tg	tbx2b		Fig. 6 from Choi et al., 2017
wnt9a^sd49/sd49; ia5Tg; s940Tg	wnt9a	Figure 3 from Paolini et al., 2021	Figure 3 from Paolini et al., 2021
wnt9a^sd49/sd49; ia5Tg; s940Tg + MO3-wnt9a		Figure 3 from Paolini et al., 2021	Figure 3 from Paolini et al., 2021

Sequence Information

Other Construct Pages

None

Citations