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ZIRC
ZFIN ID: ZDB-FIG-181113-5
Choi et al., 2017 - Bmp Signaling Governs Biliary-Driven Liver Regeneration in Zebrafish via Tbx2b and Id2a. Hepatology (Baltimore, Md.)   66(5):1616-1630 Full text @ Hepatology
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Anatomical Term:
Stage Range: Day 6 to Days 7-13
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Day 6 to Days 7-13

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
cp s931Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue ISH
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue ISH
gc s931Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue ISH
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue ISH
hnf4a s931Tg chemical ablation: hepatocyte, chemical treatment by environment: DMH1, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue RTPCR
id2a s931Tg chemical ablation: hepatocyte, chemical treatment by environment: DMH1, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue ISH
Day 6 liver regenerating tissue RTPCR
s931Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue ISH
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue ISH
mCherry s940Tg ; s931Tg ; s939Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue IHC
smad5m169/m169 ; s939Tg ; s931Tg ; s940Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue IHC
smad5 s931Tg chemical ablation: hepatocyte, chemical treatment by environment: DMH1, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue ISH
Day 6 liver regenerating tissue RTPCR
s931Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue ISH
tbx2b s931Tg chemical ablation: hepatocyte, chemical treatment by environment: DMH1, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue ISH
Day 6 liver regenerating tissue RTPCR
s931Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue ISH
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue ISH
Venus s940Tg ; s931Tg ; s939Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue IHC
smad5m169/m169 ; s939Tg ; s931Tg ; s940Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
s931Tg chemical ablation: hepatocyte, chemical treatment by environment: DMH1, chemical treatment by environment: metronidazole Day 6 liver regenerating tissue smad5 expression decreased amount, abnormal
Day 6 liver regenerating tissue hnf4a expression decreased amount, abnormal
Day 6 liver regenerating tissue tbx2b expression decreased amount, abnormal
Day 6 liver regenerating tissue id2a expression decreased amount, abnormal
Day 6 liver regenerating tissue id2a expression decreased amount, abnormal
Day 6 liver regenerating tissue smad5 expression decreased amount, abnormal
Day 6 liver regenerating tissue tbx2b expression decreased amount, abnormal
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue id2a expression decreased amount, abnormal
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue cp expression decreased amount, abnormal
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue tbx2b expression decreased amount, abnormal
s931Tg ; smad5m169/m169 chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue gc expression decreased amount, abnormal
smad5m169/m169 ; s939Tg ; s931Tg ; s940Tg chemical ablation: hepatocyte, chemical treatment by environment: metronidazole Days 7-13 liver regenerating tissue Venus expression increased amount, abnormal
Full text @ Hepatology