Gene
hdac1
- ID
- ZDB-GENE-020419-32
- Name
- histone deacetylase 1
- Symbol
- hdac1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Enables transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within with a positive effect on secondary heart field specification. Acts upstream of or within several processes, including cardiac muscle cell proliferation; digestive system development; and nervous system development. Predicted to be part of NuRD complex. Predicted to be active in nucleus. Is expressed in immature eye; nervous system; pectoral fin; and pharyngeal arch. Orthologous to human HDAC1 (histone deacetylase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101582 (9 images)
- IMAGE:6904025 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 69 figures from 24 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR023801 | Histone deacetylase domain |
| Family | IPR000286 | Histone deacetylase family |
| Family | IPR003084 | Histone deacetylase |
| Family | IPR050284 | Histone deacetylase and polyamine deacetylase |
| Homologous_superfamily | IPR023696 | Ureohydrolase domain superfamily |
| Homologous_superfamily | IPR037138 | Histone deacetylase domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Histone deacetylase | Histone deacetylase and polyamine deacetylase | Histone deacetylase domain | Histone deacetylase domain superfamily | Histone deacetylase family | Ureohydrolase domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q8JIY7 | InterPro | 480 | ||||||
| UniProtKB:A0A2R8QIW0 | InterPro | 484 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available