Gene

smad5

ID
ZDB-GENE-990603-9
Name
SMAD family member 5
Symbol
smad5 Nomenclature History
Previous Names
  • madh5
  • smd5 (1)
  • fb67b04
  • pgy (1)
  • piggytail (1)
  • sb:cb400
  • sbn
  • SMA- and MAD-related protein 5
  • somitabun
  • wu:fb67b04 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Exhibits transcription regulatory region DNA binding activity. Involved in several processes, including embryonic morphogenesis; regulation of transcription, DNA-templated; and vasculature development. Predicted to localize to cytoplasm; nucleus; and transcription factor complex. Is expressed in eye and posterior lateral line primordium. Orthologous to human SMAD5 (SMAD family member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
49 figures from 28 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With smad5 Human Ortholog
No data available
Associated With smad5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001132 SMAD domain, Dwarfin-type
Domain IPR003619 MAD homology 1, Dwarfin-type
Domain IPR013019 MAD homology, MH1
Family IPR013790 Dwarfin
Homologous_superfamily IPR008984 SMAD/FHA domain superfamily
Homologous_superfamily IPR017855 SMAD-like domain superfamily
Homologous_superfamily IPR036578 SMAD MH1 domain superfamily
Domain Details Per Protein
Protein Length Dwarfin MAD homology 1, Dwarfin-type MAD homology, MH1 SMAD domain, Dwarfin-type SMAD/FHA domain superfamily SMAD-like domain superfamily SMAD MH1 domain superfamily
UniProtKB:Q9W7E7 464
UniProtKB:A5PMC0 464
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-smad polyclonal IgG Rabbit
  • IHC
  • WB
Cell Signaling Technology, Inc.
77
Ab1-smad5 polyclonal IgG Rabbit
GeneTex
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations