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ZIRC
ZFIN ID: ZDB-GENE-990603-9
Gene Name: SMAD family member 5
Gene Symbol: smad5
Sequence Ontology ID : SO:0000704

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Previous Names: madh5, smd5 (1), fb67b04, pgy (1), piggytail (1), sb:cb400, sbn, SMA- and MAD-related protein 5, somitabun, wu:fb67b04 (1)

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits protein heterodimerization activity and transcription regulatory region DNA binding activity. Involved in several processes, including embryonic morphogenesis; regulation of transcription,  ...
GENE EXPRESSION
All Expression Data: 17 figures from 15 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55211]
  1 figure (1 image) from Thisse et al., 2005 [eu319]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b1100 Point Mutation Unknown Missense
dfr3 Point Mutation Unknown Missense ENU
dtc24 Point Mutation Unknown Missense ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • dti216c Point Mutation Unknown Missense ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • dty40 Point Mutation Unknown Missense ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fr4 Point Mutation Unknown Missense ENU
    fr5 Point Mutation Unknown Premature Stop ENU
    la027522Tg Transgenic Insertion Unknown Unknown DNA
    m169 Point Mutation Unknown Cryptic Acceptor Splice Site, Frameshift, Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14393 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • smad5_unspecified Unspecified Unknown Unknown
    st30 Point Mutation Unknown Missense ENU
    st31 Point Mutation Unknown Missense ENU
    st32 Point Mutation Unknown Missense ENU
    ta206 Unknown Unknown Unknown ENU
    tc227a Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tx223 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH smad5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH smad5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of ventral identity (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 30)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad5-201 (1) 2551
    smad5-202 (1) 894
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smad5 No data available
    MARKER RELATIONSHIPS
    smad5Contained in: [BAC] DKEYP-110E4 (1)
    smad5Contains: [SNP] rs3728635 (1), rs3728636 (1), rs3728637 (1), rs3728638 (1), rs3728639 (1), rs3728640 (1), rs3728641 (1)
    smad5Encodes: [EST] eu319 (1), fb67b04 (1)
    [cDNA] MGC:55211 (1) (order this), MGC:76817 (1) (order this), MGC:174444 (1) (order this), MGC:174796 (1) (order this), MGC:192783 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131368 (1) 2572bp
    Genomic GenBank:BX323077 (1) 195732bp
    Select Tool
    Polypeptide UniProtKB:A5PMC0 (1) 464aa
    Sequence Clusters UniGene:75335 (1)
    Sequence Information (all 48)
    ORTHOLOGY for smad5 (Chr: 14)
    CITATIONS (124)