ZFIN is now using GRCz12tu for Genomic Data
Gene
smad5
- ID
- ZDB-GENE-990603-9
- Name
- SMAD family member 5
- Symbol
- smad5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables transcription cis-regulatory region binding activity. Involved in BMP signaling pathway. Acts upstream of or within several processes, including determination of ventral identity; dorsal convergence; and tube morphogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of heteromeric SMAD protein complex. Is expressed in eye; margin; and posterior lateral line primordium. Orthologous to human SMAD5 (SMAD family member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 49 figures from 28 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | MAD homology 1, Dwarfin-type | MAD homology, MH1 | SMAD/FHA domain superfamily | SMAD-like domain superfamily | SMAD MH1 domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q9W7E7 | InterPro | 464 | |||||
| UniProtKB:A5PMC0 | InterPro | 464 |
- Genome Browsers
Interactions and Pathways
Plasmids
No data available
- Genome Browsers