ZFIN ID: ZDB-MRPHLNO-041217-12
Morpholino Name: MO1-wnt8a
Target: wnt8a (1)
Previous Names: wnt8-1MO (1), wnt8-MO1 (1), wnt8-orf1 (1)

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Sequence:
5' - ACGCAAAAATCTGGCAAGGGTTCAT - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATION
No data available
CONSTRUCTS WITH SEQUENCES FROM MO1-wnt8a No data available
GENE EXPRESSION
Gene expression in Wild Types + MO1-wnt8a
Expressed Gene Anatomy Figures
dand5 Fig. 2 with image from Lin et al., 2009
egr2b Fig. 3 with image from Rhinn et al., 2009
enc3 Fig. 4 with image from Qian et al., 2013
foxd3 Fig. 3 with image from Dutta et al., 2010
gbx1 Fig. 5 with image from Rhinn et al., 2005
otx2b Fig. 3 with image from Rhinn et al., 2009
Fig. 5 with image from Rhinn et al., 2005
tbxta Fig. 5 with image from Rhinn et al., 2005
znf703 Fig. 4 with image from Dutta et al., 2015
PHENOTYPE
Phenotype resulting from MO1-wnt8a
Phenotype of all Fish created by or utilizing MO1-wnt8a
Phenotype Fish Conditions Figures
whole organism decreased length, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
tail bud decreased length, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
tail bud morphology, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
post-vent region decreased length, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
post-anal tail morphogenesis disrupted, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
heart looping disrupted, abnormal TL + MO1-wnt8a standard conditions Fig. 1 with image from Lin et al., 2009
Kupffer's vesicle cilium decreased length, abnormal TL + MO1-wnt8a standard conditions Fig. 2 with image from Lin et al., 2009
embryonic heart tube left/right pattern formation disrupted, abnormal TL + MO1-wnt8a standard conditions Fig. 1 with imageFig. 3 with image from Lin et al., 2009
telencephalon increased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
Fig. 3 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
pronephric tubule cell increased distance pronephric tubule cell, abnormal TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: aphidicolin, chemical treatment by environment: hydroxyurea Fig. 7 with image from Naylor et al., 2017
tail bud protruding, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
pronephric tubule distal region slc12a3 expression decreased distribution, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 7 with image from Naylor et al., 2017
common myeloid progenitor spi1b expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 8 with image from Naylor et al., 2017
pronephric tubule cell increased distance pronephric tubule cell, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 7 with image from Naylor et al., 2017
pronephric tubule distal region slc12a3 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 7 with image from Naylor et al., 2017
pronephric tubule proximal region has number of cell, ameliorated TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
post-vent region decreased length, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
pronephric tubule cell population proliferation decreased occurrence, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 6 with image from Naylor et al., 2017
whole organism decreased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
whole organism wholly dorsalized, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
whole organism wholly anterioralized, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Gan et al., 2008
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
whole organism shape, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
shield increased width, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Li et al., 2011
erythroid lineage cell gata1a expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 8 with image from Naylor et al., 2017
pronephric tubule proximal region has fewer parts of type cell, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 3 with image from Naylor et al., 2017
post-vent region decreased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
pronephros pax2a expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 3 with image from Naylor et al., 2017
pronephric tubule Ab1-hnf1b labeling decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 3 with image from Naylor et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
trunk decreased length, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
pronephric tubule Ab1-hnf1b labeling amount, ameliorated TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
caudal fin morphology, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
head increased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Gan et al., 2008
trunk posterior region absent, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
histone methyltransferase activity (H4-K20 specific) disrupted, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
pronephros pax2a expression amount, ameliorated TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
caudal fin absent, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
pronephric tubule slc12a3 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Naylor et al., 2017
apoptotic process decreased occurrence, abnormal TU + MO1-wnt8a + MO2-wnt8a + MO4-tp53 standard conditions Fig. 4 with image from Naylor et al., 2017
pronephric tubule slc12a3 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a + MO4-tp53 standard conditions Fig. 4 with image from Naylor et al., 2017
whole organism posterior region ab1-casp3 labeling decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a + MO4-tp53 standard conditions Fig. 4 with image from Naylor et al., 2017
neural keel wholly anterioralized, abnormal WT + MO1-wnt8a standard conditions Fig. 3 with image from Rhinn et al., 2009
whole organism znf703 expression absent, abnormal WT + MO1-wnt8a standard conditions Fig. 4 with image from Dutta et al., 2015
neural crest cell morphology, abnormal WT + MO1-wnt8a standard conditions Fig. 3 with image from Dutta et al., 2010
presumptive neural plate wholly anterioralized, abnormal WT + MO1-wnt8a standard conditions Fig. 3 with image from Rhinn et al., 2009
neural crest cell differentiation disrupted, abnormal WT + MO1-wnt8a standard conditions Fig. 3 with image from Dutta et al., 2010
midbrain decreased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
presumptive mesoderm wholly dorsalized, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 from Lekven et al., 2001
forebrain increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
forebrain prominent, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
whole organism wholly dorsalized, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 with image from Wylie et al., 2014
somite decreased amount, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
post-vent region decreased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
post-vent region decreased length, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
Fig. 7 from Lekven et al., 2001
whole organism dorsal region gsc expression increased distribution, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Kagermeier-Schenk et al., 2011
head increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
telencephalon increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
eye increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
embryonic pattern specification disrupted, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 from Lekven et al., 2001
presumptive neural plate wholly anterioralized, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 from Lekven et al., 2001
margin tpbga expression decreased distribution, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
post-vent region kinked, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region has fewer parts of type somite, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
trunk decreased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
forebrain distended, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
whole organism posterior region absent, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
presumptive telencephalon foxg1a expression increased distribution, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Kagermeier-Schenk et al., 2011
post-vent region curved ventral, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
whole organism dead, abnormal WT + MO1-wnt8a + MO2-wnt8a + MO7-wnt8a standard conditions Fig. 6 with image from Wylie et al., 2014
whole organism wholly dorsalized, abnormal WT + MO1-wnt8a + MO2-wnt8a + MO7-wnt8a standard conditions Fig. 6 with image from Wylie et al., 2014
canonical Wnt signaling pathway decreased process quality, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
post-vent region aplastic, abnormal tbx16b104/b104 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
somite aplastic, abnormal tbx16b104/b104 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
trunk aplastic, abnormal tbx16b104/b104 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
trunk aplastic, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
somite structure, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
somite decreased amount, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
somite fused with somite, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
post-vent region aplastic, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a(AB) standard conditions Fig. 7 from Lekven et al., 2001
tail bud decreased length, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
somite decreased amount, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
post-anal tail morphogenesis disrupted, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
notochord truncated, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
central canal dilated, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
tail bud bent, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
post-vent region decreased length, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
whole organism decreased length, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
tail bud morphology, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
Kupffer's vesicle cilium decreased length, abnormal TL + MO1-wnt3a + MO1-wnt8a standard conditions Fig. 2 with image from Lin et al., 2009
embryonic heart tube left/right pattern formation disrupted, abnormal TL + MO1-wnt3a + MO1-wnt8a standard conditions Fig. 1 with image from Lin et al., 2009
heart looping disrupted, abnormal TL + MO1-wnt3a + MO1-wnt8a standard conditions Fig. 1 with image from Lin et al., 2009
canonical Wnt signaling pathway decreased process quality, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
post-vent region decreased length, abnormal TU + MO1-kmt5aa + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
telencephalon increased size, abnormal TU + MO1-kmt5aa + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
trunk decreased length, abnormal TU + MO1-kmt5aa + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
whole organism wholly anterioralized, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
telencephalon increased size, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
head decreased size, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
post-vent region decreased size, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
post-vent region has fewer parts of type somite, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region truncated, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
head increased size, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region decreased length, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region kinked, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region decreased length, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
head increased size, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region has fewer parts of type somite, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region kinked, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
post-vent region truncated, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Table 1 from Shimizu et al., 2005
head truncated, abnormal WT + MO1-foxa3 + MO1-gsc + MO1-wnt8a standard conditions Fig. 6 with image from Seiliez et al., 2006
eye fused with eye, abnormal WT + MO1-foxa3 + MO1-gsc + MO1-wnt8a standard conditions Fig. 6 with image from Seiliez et al., 2006
Genome Resources: MODB:36 (2)
CITATIONS (45)