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ZFIN ID: ZDB-FISH-150901-17010
Fish name: TU + MO1-wnt8a + MO2-wnt8a
Genotype: TU
Targeting Reagent: MO1-wnt8a, MO2-wnt8a
HUMAN DISEASE MODELED by TU + MO1-wnt8a + MO2-wnt8a
No data available
GENE EXPRESSION
Gene expression in TU + MO1-wnt8a + MO2-wnt8a
RNA expression
Expressed Gene Structure Conditions Figures
cdx4 standard conditions Fig. 4 with image from He et al., 2017
Fig. 4 with image from Li et al., 2011
Fig. 4 from Ding et al., 2008
eve1 standard conditions Fig. 4 from Ding et al., 2008
gata1a control Fig. 8 with image from Naylor et al., 2017
gsc standard conditions Fig. 4 with image from Li et al., 2011
Fig. 4 from Ding et al., 2008
kdrl control Fig. 8 with image from Naylor et al., 2017
myod1 standard conditions Fig. 4 from Ding et al., 2008
pax2a chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
standard conditions Fig. 3 with image from Naylor et al., 2017
Fig. 4 from Ding et al., 2008
slc4a4a control Fig. 7 with image from Naylor et al., 2017
slc12a3 standard conditions Fig. 4 with imageFig. 7 with image from Naylor et al., 2017
spi1b control Fig. 8 with image from Naylor et al., 2017
tbx6 control Fig. 4 with image from He et al., 2017
tbx16l standard conditions Fig. 4 with image from Li et al., 2011
Fig. 4 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
tbxta standard conditions Fig. 4 with image from Li et al., 2011
Fig. 4 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
vox standard conditions Fig. 3 from Gan et al., 2008
zic1 standard conditions Fig. 3 with image from Li et al., 2011
Fig. 4 from Ding et al., 2008
Reporter gene expression No data available
PHENOTYPE
Phenotype in TU + MO1-wnt8a + MO2-wnt8a
Phenotype Conditions Figures
canonical Wnt signaling pathway decreased process quality, abnormal control Fig. 4 with image from He et al., 2017
caudal fin absent, abnormal standard conditions Fig. 2 with image from Naylor et al., 2017
caudal fin morphology, abnormal standard conditions Fig. 2 with image from Naylor et al., 2017
common myeloid progenitor spi1b expression decreased amount, abnormal control Fig. 8 with image from Naylor et al., 2017
erythroid lineage cell gata1a expression decreased amount, abnormal control Fig. 8 with image from Naylor et al., 2017
head increased size, abnormal standard conditions Fig. 3 from Gan et al., 2008
histone methyltransferase activity (H4-K20 specific) disrupted, abnormal standard conditions Fig. 3 with image from Li et al., 2011
post-vent region decreased length, abnormal standard conditions Fig. 3 with image from Li et al., 2011
post-vent region decreased size, abnormal standard conditions Fig. 3 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal control Fig. 4 with image from He et al., 2017
pronephric tubule Ab1-hnf1b labeling amount, ameliorated chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
pronephric tubule slc12a3 expression decreased amount, abnormal standard conditions Fig. 4 with image from Naylor et al., 2017
pronephric tubule Ab1-hnf1b labeling decreased amount, abnormal control Fig. 3 with image from Naylor et al., 2017
pronephric tubule cell increased distance pronephric tubule cell, abnormal chemical treatment by environment: aphidicolin, chemical treatment by environment: hydroxyurea Fig. 7 with image from Naylor et al., 2017
pronephric tubule cell increased distance pronephric tubule cell, abnormal control Fig. 7 with image from Naylor et al., 2017
pronephric tubule cell population proliferation decreased occurrence, abnormal control Fig. 6 with image from Naylor et al., 2017
pronephric tubule distal region slc12a3 expression decreased amount, abnormal control Fig. 7 with image from Naylor et al., 2017
pronephric tubule distal region slc12a3 expression decreased distribution, abnormal control Fig. 7 with image from Naylor et al., 2017
pronephric tubule proximal region has fewer parts of type cell, abnormal control Fig. 3 with image from Naylor et al., 2017
pronephric tubule proximal region has number of cell, ameliorated chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
pronephros pax2a expression amount, ameliorated chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
pronephros pax2a expression decreased amount, abnormal control Fig. 3 with image from Naylor et al., 2017
shield increased width, abnormal standard conditions Fig. 4 with image from Li et al., 2011
tail bud protruding, abnormal standard conditions Fig. 3 from Ding et al., 2008
telencephalon increased size, abnormal standard conditions Fig. 3 with image from Li et al., 2011
Fig. 3 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
trunk decreased length, abnormal standard conditions Fig. 3 with image from Li et al., 2011
trunk posterior region absent, abnormal standard conditions Fig. 2 with image from Naylor et al., 2017
whole organism decreased size, abnormal standard conditions Fig. 2 with image from Naylor et al., 2017
whole organism shape, abnormal standard conditions Fig. 3 from Ding et al., 2008
whole organism wholly anterioralized, abnormal standard conditions Fig. 3 from Gan et al., 2008
whole organism wholly dorsalized, abnormal standard conditions Fig. 3 from Ding et al., 2008

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