ZFIN ID: ZDB-FIG-101215-8
Lekven et al., 2001 - Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning. Developmental Cell   1(1):103-114 Full text @ Dev. Cell
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 20-25 somites to Prim-5

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
Df(Chr14:wnt8a)w8/+; T(Chr14:wnt8a)w11/+ standard conditions Prim-5 forebrain apoptotic, abnormal
Prim-5 notochord increased width, abnormal
Prim-5 post-vent region aplastic, abnormal
Prim-5 somite decreased amount, abnormal
Prim-5 somite structure, abnormal
Prim-5 trunk aplastic, abnormal
Prim-5 whole organism wholly anterioralized, abnormal
WT + MO1-wnt8a standard conditions Prim-5 whole organism morphology, normal
WT + MO1-wnt8a + MO2-wnt8a standard conditions Prim-5 forebrain prominent, abnormal
Prim-5 midbrain decreased size, abnormal
Prim-5 post-vent region decreased size, abnormal
Prim-5 somite decreased amount, abnormal
Prim-5 trunk decreased size, abnormal
WT + MO1-wnt8a + MO2-wnt8a standard conditions 20-25 somites forebrain distended, abnormal
20-25 somites post-vent region decreased length, abnormal
20-25 somites somite decreased amount, abnormal
WT + MO2-wnt8a standard conditions Prim-5 brain poorly differentiated, abnormal
Prim-5 forebrain apoptotic, abnormal
Prim-5 notochord undulate, abnormal
tbx16b104/b104 (AB) standard conditions Prim-5 post-vent region somite present, normal
Prim-5 trunk somite aplastic, abnormal
tbx16b104/b104 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Prim-5 post-vent region aplastic, abnormal
Prim-5 somite aplastic, abnormal
Prim-5 trunk aplastic, abnormal
tbxtab160/b160 (AB) standard conditions 20-25 somites post-vent region decreased length, abnormal
20-25 somites somite decreased amount, abnormal
20-25 somites somite fused with somite, abnormal
tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions 20-25 somites post-vent region aplastic, abnormal
20-25 somites somite decreased amount, abnormal
20-25 somites somite fused with somite, abnormal
20-25 somites somite structure, abnormal
20-25 somites trunk aplastic, abnormal
Full text @ Dev. Cell