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General Information
ZIRC
ZFIN ID: ZDB-FIG-190910-40
Sánchez et al., 2018 - Pla2g6 Deficiency in Zebrafish Leads to Dopaminergic Cell Death, Axonal Degeneration, Increased β-Synuclein Expression, and Defects in Brain Functions and Pathways. Molecular neurobiology   55(8):6734-6754 Full text @ Mol. Neurobiol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage Range: 14-19 somites to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 14-19 somites to Protruding-mouth

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
adar TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
agrn TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
atp1a3a TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
cacna2d4b TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
casp8 TL standard conditions 14-19 somites whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions 14-19 somites whole organism RTPCR
ccng1 TL standard conditions 14-19 somites whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions 14-19 somites whole organism RTPCR
grin1b TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
hsp70l TL standard conditions 14-19 somites whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions 14-19 somites whole organism RTPCR
hsp90aa1.2 TL standard conditions 14-19 somites whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions 14-19 somites whole organism RTPCR
hspb1 TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
huwe1 TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
kif5c TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
lmna TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
mfn2 TL standard conditions 14-19 somites whole organism RTPCR
Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions 14-19 somites whole organism RTPCR
Protruding-mouth whole organism RTPCR
npc1 TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
slc2a1a TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
sptbn2 TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
uchl1 TL standard conditions 14-19 somites whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions 14-19 somites whole organism RTPCR
unc13a TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
xpr1a TL standard conditions Protruding-mouth whole organism RTPCR
TL + MO1-pla2g6 + MO4-tp53 standard conditions Protruding-mouth whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TL + MO1-pla2g6 + MO4-tp53 standard conditions 14-19 somites whole organism hsp90aa1.2 expression increased amount, abnormal
14-19 somites whole organism uchl1 expression increased amount, abnormal
14-19 somites whole organism ccng1 expression increased amount, abnormal
14-19 somites whole organism hsp70l expression increased amount, abnormal
14-19 somites whole organism mfn2 expression increased amount, abnormal
14-19 somites whole organism casp8 expression increased amount, abnormal
Protruding-mouth whole organism agrn expression decreased amount, abnormal
Protruding-mouth whole organism cacna2d4b expression decreased amount, abnormal
Protruding-mouth whole organism mfn2 expression decreased amount, abnormal
Protruding-mouth whole organism npc1 expression decreased amount, abnormal
Protruding-mouth whole organism atp1a3a expression decreased amount, abnormal
Protruding-mouth whole organism adar expression decreased amount, abnormal
Protruding-mouth whole organism sptbn2 expression decreased amount, abnormal
Protruding-mouth whole organism unc13a expression decreased amount, abnormal
Protruding-mouth whole organism xpr1a expression decreased amount, abnormal
Protruding-mouth whole organism huwe1 expression decreased amount, abnormal
Protruding-mouth whole organism kif5c expression decreased amount, abnormal
Protruding-mouth whole organism lmna expression decreased amount, abnormal
Protruding-mouth whole organism slc2a1a expression decreased amount, abnormal
Protruding-mouth whole organism grin1b expression decreased amount, abnormal
Protruding-mouth whole organism hspb1 expression increased amount, abnormal
Full text @ Mol. Neurobiol.