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General Information
ZIRC
ZFIN ID: ZDB-FISH-190911-1
Fish name: TL + MO1-pla2g6 + MO4-tp53
Genotype: TL
Targeting Reagent: MO4-tp53, MO1-pla2g6
HUMAN DISEASE MODELED by TL + MO1-pla2g6 + MO4-tp53
No data available
GENE EXPRESSION
Gene expression in TL + MO1-pla2g6 + MO4-tp53
RNA expression
Expressed Gene Structure Conditions Figures
adar standard conditions Fig. 7 from Sánchez et al., 2018
agrn standard conditions Fig. 7 from Sánchez et al., 2018
atp1a3a standard conditions Fig. 7 from Sánchez et al., 2018
cacna2d4b standard conditions Fig. 7 from Sánchez et al., 2018
casp8 standard conditions Fig. 7 from Sánchez et al., 2018
ccng1 standard conditions Fig. 7 from Sánchez et al., 2018
grin1b standard conditions Fig. 7 from Sánchez et al., 2018
hsp70l standard conditions Fig. 7 from Sánchez et al., 2018
hsp90aa1.2 standard conditions Fig. 7 from Sánchez et al., 2018
hspb1 standard conditions Fig. 7 from Sánchez et al., 2018
huwe1 standard conditions Fig. 7 from Sánchez et al., 2018
kif5c standard conditions Fig. 7 from Sánchez et al., 2018
lmna standard conditions Fig. 7 from Sánchez et al., 2018
mfn2 standard conditions Fig. 7 from Sánchez et al., 2018
npc1 standard conditions Fig. 7 from Sánchez et al., 2018
pla2g6 standard conditions Fig. 1 from Sánchez et al., 2018
slc2a1a standard conditions Fig. 7 from Sánchez et al., 2018
slc6a3 standard conditions Fig. 2 from Sánchez et al., 2018
sncb standard conditions Fig. 2 from Sánchez et al., 2018
sptbn2 standard conditions Fig. 7 from Sánchez et al., 2018
th standard conditions Fig. 2 from Sánchez et al., 2018
th2 standard conditions Fig. 2 from Sánchez et al., 2018
uchl1 standard conditions Fig. 7 from Sánchez et al., 2018
unc13a standard conditions Fig. 7 from Sánchez et al., 2018
xpr1a standard conditions Fig. 7 from Sánchez et al., 2018
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab1-tuba control Fig. 4Fig. 5 from Sánchez et al., 2018
Reporter gene expression No data available
PHENOTYPE
Phenotype in TL + MO1-pla2g6 + MO4-tp53
Phenotype Conditions Figures
brain pla2g6 expression decreased amount, abnormal standard conditions Fig. 1 from Sánchez et al., 2018
brain malformed, abnormal standard conditions Fig. 1 from Sánchez et al., 2018
diencephalon th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
diencephalon has fewer parts of type dopaminergic neuron, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
endohypothalamic tract th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
forebrain sncb expression increased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
forebrain axon defasciculated, abnormal control Fig. 4Fig. 5 from Sánchez et al., 2018
forebrain axonal fasciculation decreased occurrence, abnormal control Fig. 4Fig. 5 from Sánchez et al., 2018
habenula sncb expression increased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
hindbrain has fewer parts of type dopaminergic neuron, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
hindbrain sncb expression increased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
hypothalamus posterior region th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
locus coeruleus th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
medulla oblongata th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
midbrain has fewer parts of type dopaminergic neuron, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
midbrain sncb expression increased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
midbrain axon defasciculated, abnormal control Fig. 4Fig. 5 from Sánchez et al., 2018
midbrain axonal fasciculation decreased occurrence, abnormal control Fig. 4Fig. 5 from Sánchez et al., 2018
olfactory bulb th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
peripheral nervous system has fewer parts of type peripheral neuron, abnormal control Fig. 4 from Sánchez et al., 2018
post-vent region curled, abnormal standard conditions Fig. 1 from Sánchez et al., 2018
posterior lateral line ganglion sncb expression increased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
pretectum th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
spinal cord malformed, abnormal control Fig. 4 from Sánchez et al., 2018
statoacoustic (VIII) ganglion sncb expression increased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
telencephalon has fewer parts of type dopaminergic neuron, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
trigeminal ganglion decondensed, abnormal control Fig. 4 from Sánchez et al., 2018
trigeminal ganglion disorganized, abnormal control Fig. 5 from Sánchez et al., 2018
trigeminal ganglion increased length, abnormal control Fig. 4 from Sánchez et al., 2018
trigeminal ganglion increased width, abnormal control Fig. 4 from Sánchez et al., 2018
whole organism slc6a3 expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
whole organism atp1a3a expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism cacna2d4b expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism sptbn2 expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism mfn2 expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism grin1b expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism xpr1a expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism adar expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism unc13a expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism agrn expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism pla2g6 expression decreased amount, abnormal standard conditions Fig. 1 from Sánchez et al., 2018
whole organism th2 expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
whole organism lmna expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism slc2a1a expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism kif5c expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism npc1 expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism huwe1 expression decreased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism th expression decreased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
whole organism decreased size, abnormal standard conditions Fig. 1 from Sánchez et al., 2018
whole organism hspb1 expression increased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism sncb expression increased amount, abnormal standard conditions Fig. 2 from Sánchez et al., 2018
whole organism uchl1 expression increased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism hsp70l expression increased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism mfn2 expression increased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism hsp90aa1.2 expression increased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism ccng1 expression increased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018
whole organism casp8 expression increased amount, abnormal standard conditions Fig. 7 from Sánchez et al., 2018

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