ZFIN Figure: Chernyavskaya et al., 2017, Fig. 3

ZFIN ID: ZDB-FIG-180724-8

ZFIN ID: ZDB-FIG-180724-8

Chernyavskaya et al., 2017 - Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (Cambridge, England) 144(16):2925-2939 Full text @ Development

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	ifng1 ifnphi1 irf7 irf9 isg15 mxa nfkb2 stat1a stat1b tnfa
Fish:	uhrf1^{hi272Tg/hi272Tg}
Anatomical Term:	whole organism
Stage Range:	Long-pec to Day 5

PHENOTYPE:

Fish:	uhrf1^{hi272Tg/hi272Tg}
Observed In:	whole organism
Stage Range:	Long-pec to Day 5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
ifng1	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
ifnphi1	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
irf7	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
irf9	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
isg15	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
mxa	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
nfkb2	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
stat1a	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
stat1b	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR
tnfa	uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism	RTPCR
			Protruding-mouth	whole organism	RTPCR
			Day 5	whole organism	RTPCR

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
uhrf1^{hi272Tg/hi272Tg}	standard conditions	Long-pec	whole organism ifnphi1 expression increased amount, abnormal
		Long-pec	whole organism nfkb2 expression increased amount, abnormal
		Protruding-mouth	whole organism ifnphi1 expression increased amount, abnormal
		Protruding-mouth	whole organism irf7 expression increased amount, abnormal
		Protruding-mouth	whole organism irf9 expression increased amount, abnormal
		Protruding-mouth	whole organism isg15 expression increased amount, abnormal
		Protruding-mouth	whole organism mxa expression increased amount, abnormal
		Protruding-mouth	whole organism nfkb2 expression increased amount, abnormal
		Protruding-mouth	whole organism stat1a expression increased amount, abnormal
		Protruding-mouth	whole organism stat1b expression increased amount, abnormal
		Day 5	whole organism ifnphi1 expression increased amount, abnormal
		Day 5	whole organism irf7 expression increased amount, abnormal
		Day 5	whole organism irf9 expression increased amount, abnormal
		Day 5	whole organism isg15 expression increased amount, abnormal
		Day 5	whole organism mxa expression increased amount, abnormal
		Day 5	whole organism nfkb2 expression increased amount, abnormal
		Day 5	whole organism stat1a expression increased amount, abnormal
		Day 5	whole organism stat1b expression increased amount, abnormal

Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development