Gene

mxa

ID
ZDB-GENE-030721-5
Name
myxovirus (influenza) resistance A
Symbol
mxa Nomenclature History
Previous Names
  • mx (1)
  • fj23d12
  • wu:fj23d12
  • zgc:136725
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have GTPase activity and microtubule binding activity. Involved in response to arsenic-containing substance; response to bacterium; and response to virus. Predicted to localize to several cellular components, including dendritic spine head; postsynaptic density; and postsynaptic endocytic zone membrane. Is expressed in several structures, including gill; heart; immune system; liver; and muscle. Orthologous to human MX1 (MX dynamin like GTPase 1) and MX2 (MX dynamin like GTPase 2).
Genome Resources
Note
None
Expression
All Expression Data
14 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mxa Human Ortholog
No data available
Associated With mxa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019762 Dynamin, GTPase region, conserved site
Domain IPR000375 Dynamin central domain
Domain IPR001401 Dynamin, GTPase domain
Domain IPR003130 Dynamin GTPase effector
Domain IPR020850 GTPase effector domain
Domain IPR030381 Dynamin-type guanine nucleotide-binding (G) domain
Family IPR022812 Dynamin superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Dynamin central domain Dynamin, GTPase domain Dynamin GTPase effector Dynamin, GTPase region, conserved site Dynamin superfamily Dynamin-type guanine nucleotide-binding (G) domain GTPase effector domain P-loop containing nucleoside triphosphate hydrolase
UniProtKB:B8JKI3 632
UniProtKB:Q8JH68 646
UniProtKB:Q1ECX1 632
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations