Gene
isg15
- ID
- ZDB-GENE-021211-1
- Name
- ISG15 ubiquitin like modifier
- Symbol
- isg15 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have protein tag and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ISG15 (ISG15 ubiquitin like modifier).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 38 | Alliance | Immunodeficiency 38 | 616126 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ubiquitin and ubiquitin-like | Ubiquitin domain | Ubiquitin-like domain | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A2BHB8
|
157 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available