Gene

ifng1

ID
ZDB-GENE-040629-1
Name
interferon gamma 1
Symbol
ifng1 Nomenclature History
Previous Names
  • ifng1-2
  • Ifng2 (1)
  • ifng
  • Ifngamma2 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have interferon-gamma receptor binding activity. Involved in several processes, including defense response to bacterium; endothelial to hematopoietic transition; and response to virus. Predicted to localize to extracellular region. Is expressed in axial vasculature; blood; digestive system; pleuroperitoneal region; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including allergic rhinitis; ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; and leukemia (multiple). Orthologous to human IFNG (interferon gamma).
Genome Resources
Note
None
Expression
All Expression Data
42 figures from 29 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ifng1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aplastic anemia Alliance {Aplastic anemia} 609135
immunodeficiency 69 Alliance ?Immunodeficiency 69, mycobacteriosis 618963
tuberous sclerosis 2 Alliance {TSC2 angiomyolipomas, renal, modifier of} 613254
{AIDS, rapid progression to} 609423
{Hepatitis C virus, response to therapy of} 609532
{Tuberculosis, protection against} 607948
Associated With ifng1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002069 Interferon gamma
Homologous_superfamily IPR009079 Four-helical cytokine-like, core
Domain Details Per Protein
Protein Length Four-helical cytokine-like, core Interferon gamma
UniProtKB:Q5RHV5 179
UniProtKB:Q75S22 185
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ifng1-2 monoclonal
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations