FIGURE

Fig. 5

ID

ZDB-FIG-170921-100

Publication

Chernyavskaya et al., 2017 - Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

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Fig. 5

Interferon target genes are induced in the head, jaw and liver in uhrf1 mutants. ISH for irf1b and isg15, two of the most upregulated interferon genes, in 80 and 120 hpf uhrf1 and WT siblings (3-6 embryos per group/per time point). Staining is particularly intense along the caudomedial edge of the optic tectum (white arrowhead), ear (asterisk) and liver (black arrowhead) at 120 hpf for both genes. n=15, clutches=3.

Expression Data

Genes:	irf1b isg15
Fish:	WT uhrf1^{hi272Tg/hi272Tg}
Anatomical Terms:	gut head inner ear liver mandibular arch skeleton optic tectum
Stage Range:	Protruding-mouth to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	uhrf1^{hi272Tg/hi272Tg}
Observed In:	gut head inner ear liver mandibular arch skeleton optic tectum
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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