FIGURE

Fig. S4

ID

ZDB-FIG-161201-11

Publication

Shin et al., 2016 - Vegfa signals through ERK to promote angiogenesis, but not artery differentiation

Other Figures

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Fig. S4

Artery marker gene expression following ERK inhibition. (A) Expresion of efnb2a in embryos treated with indicated compounds from 17 hpf (15 somite stage) to 25 hpf. (B) Confocal images of embryos at 30 hpf bearing indicated transgenes. Myc staining of nTom cells is red and EphrinB2 is in green. Arrows denote dusp6dm-expressing cell expressing EphrinB2. The stained structure ventral to the dorsal aorta is the pronephric duct (pnd) (C-J) Whole mount in situ hybridization with indicated riboprobes. Chemical treatment is indicated at top, stage of treatment at right. Embryos were fixed immediately following treatment. Arrows indicate position of the dorsal aorta.

Expression Data

Genes:	dll4 efnb2a flt4 hey2 kdrl notch1b
Fish:	WT
Conditions:	chemical treatment by environment: SL-327 chemical treatment by environment: semaxanib
Anatomical Terms:	dorsal aorta intersegmental vessel
Stage Range:	Prim-5 to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: SL-327 chemical treatment by environment: semaxanib
Observed In:	dorsal aorta intersegmental vessel
Stage Range:	Prim-5 to Prim-15

Phenotype Detail

Acknowledgments

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