ZFIN is now using GRCz12tu for Genomic Data
Gene
efnb2a
- ID
- ZDB-GENE-990415-67
- Name
- ephrin-B2a
- Symbol
- efnb2a Nomenclature History
- Previous Names
-
- efnb2
- ephrin-B2a
- id:ibd5072
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ephrin receptor binding activity. Acts upstream of or within several processes, including angioblast cell migration involved in selective angioblast sprouting; nervous system development; and optic vesicle morphogenesis. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse and presynaptic membrane. Is expressed in several structures, including germ ring; hindbrain neural keel; immature eye; nervous system; and vasculature. Human ortholog(s) of this gene implicated in colon carcinoma; colorectal carcinoma; and esophagus squamous cell carcinoma. Orthologous to human EFNB2 (ephrin B2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 218 figures from 154 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu689 (33 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cupredoxin | Ephrin | Ephrin-B ectodomain | Ephrin, conserved site | Ephrin receptor-binding domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:B0CLY3 | InterPro | 332 | |||||
| UniProtKB:O73874 | InterPro | 332 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
efnb2a-201
(1)
|
Ensembl | 4,598 nt | ||
| ncRNA |
efnb2a-002
(1)
|
Ensembl | 534 nt | ||
| ncRNA |
efnb2a-003
(1)
|
Ensembl | 840 nt |
Interactions and Pathways
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-efnb2 | polyclonal | IgG | Goat |
|
R&D Systems
|
11 |
Plasmids
No data available
- Genome Browsers