FIGURE

Fig. 5

ID

ZDB-FIG-140617-18

Publication

Flasse et al., 2013 - Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish

Other Figures

(all 16)

All Figure Page

Back to All Figure Page

Fig. 5

Impaired endocrine cell differentiation in neurod1 morphants. Ventral views with anterior to the left of WISH showing expression of insulin(A-C), somatostatin(D-F), ghrelin(G-I) and glucagon(J-L) in control (A, D, G, J), Mo1-neurod1(B, E, H, K) and Mo2-neurod1(C, F, I, L) morphants at 30 hpf. The quantifications on the right side of the figure represent the number of positive cells per embryo for controls and neurod1 morphants. Asterisks (***) indicate that the difference between cell number in controls and neurod1 morphants is statistically significant by Student?s t-test (P <0.001). Scale bars : 50 µm hpf, hours post fertilization; WISH, whole-mount in situ hybridization.

Expression Data

Genes:	gcga ghrl ins sst2
Fish:	WT WT + MO2-neurod1 WT + MO3-neurod1
Knockdown Reagents:	MO2-neurod1 MO3-neurod1
Anatomical Term:	pancreatic bud
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-neurod1 WT + MO3-neurod1
Knockdown Reagents:	MO2-neurod1 MO3-neurod1
Observed In:	endocrine pancreas development
Stage:	Prim-15

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Biol.