Gene

ghrl

ID
ZDB-GENE-070622-2
Name
ghrelin/obestatin prepropeptide
Symbol
ghrl Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have growth hormone-releasing hormone activity. Involved in several processes, including chordate embryonic development; regulation of response to food; and response to food. Predicted to localize to extracellular region. Is expressed in several structures, including diencephalon; digestive system; ghrelin secreting cell; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in diabetic neuropathy; morbid obesity; obesity; and type 2 diabetes mellitus. Orthologous to human GHRL (ghrelin and obestatin prepropeptide).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
39 figures from 22 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ghrl Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
obesity Alliance {Obesity, susceptibility to} 601665
Associated With ghrl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006737 Motilin/ghrelin-associated peptide
Family IPR005441 Preproghrelin peptide
Domain Details Per Protein
Protein Length Motilin/ghrelin-associated peptide Preproghrelin peptide
UniProtKB:F1QKX9 104
UniProtKB:Q3ZV42 104
UniProtKB:D0EW40 104
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-ghrl monoclonal Mouse
  • IHC
Phoenix Pharmaceuticals, Inc.
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations