Gene

gcga

ID
ZDB-GENE-010219-1
Name
glucagon a
Symbol
gcga Nomenclature History
Previous Names
  • gcg (1)
  • GLP-1 (1)
  • glu
  • zgc:103616
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Exhibits glucagon receptor binding activity. Involved in response to starvation and type B pancreatic cell development. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in Alzheimer's disease and prediabetes syndrome. Is expressed in digestive system; endocrine system; and endoderm. Orthologous to human GCG (glucagon).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
96 figures from 53 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gcga Human Ortholog
No data available
Associated With gcga Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000532 Glucagon/GIP/secretin/VIP
Family IPR015550 Glucagon
Domain Details Per Protein
Protein Length Glucagon Glucagon/GIP/secretin/VIP
UniProtKB:F1RD10 121
UniProtKB:A0A0R4IS85 176
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gcga-201 (1) Ensembl 1,766 nt
mRNA gcga-202 (1) Ensembl 820 nt
mRNA gcga-203 (1) Ensembl 997 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations